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Rational Design, Synthesis, and Crystallographic Analysis of a Hydroxyethylene-Based HIV-1 Protease Inhibitor Containing a Heterocyclic P1'-P2' Amide Bond Isostere
by
Thompson, Scott K
,
Murthy, Krishna H. M
,
Zhao, Baoguang
,
Winborne, Evon
,
Green, David W
,
Fisher, Seth M
,
DesJarlais, Renee L
,
Tomaszek, Thaddeus A. Jr
,
Meek, Thomas D
Published in
Journal of medicinal chemistry
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Polymorphous crystallization and diffraction of threonine deaminase from Escherichia coli
by
Gallagher, D. Travis
,
Eisenstein, Edward
,
Fisher, Kathryn E.
,
Zondlo, James
,
Chinchilla, Diana
,
Yu, Hoon Dae
,
Dill, Jonathan
,
Winborne, Evon
,
Ducote, Karin
,
Xiao, Gaoyi
,
Gilliland, Gary L.
Published in
Acta crystallographica. Section D, Biological crystallography.
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Binding interactions of human interleukin 5 with its receptor alpha subunit. Large scale production, structural, and functional studies of Drosophila-expressed recombinant proteins
by
Johanson, K
,
Appelbaum, E
,
Doyle, M
,
Hensley, P
,
Zhao, B
,
Abdel-Meguid, S S
,
Young, P
,
Cook, R
,
Carr, S
,
Matico, R
Published in
The Journal of biological chemistry
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Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis
by
Abdel-Meguid, Sherin S
,
Zhao, Baoguang
,
Murthy, Krishna H. M
,
Winborne, Evon
,
Choi, Joong Kwon
,
DesJarlais, Renee L
,
Minnich, Michael D
,
Culp, Jeffrey S
,
Debouck, Christine
Published in
Biochemistry (Easton)
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The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two dis...
by
MURTHY, K. H. M
,
WINBORNE, E. L
,
MINNICH, M. D
,
CULP, J. S
,
DEBOUCK, C
Published in
The Journal of biological chemistry
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An Orally Bioavailable HIV-1 Protease Inhibitor Containing an Imidazole-Derived Peptide Bond Replacement: Crystallographic and Pharmacokinetic Analysis
by
Abdel-Meguid, Sherin S
,
Metcalf, Brian W
,
Carr, Thomas J
,
Demarsh, Peter
,
DesJarlais, Renee L
,
Fisher, Seth
,
Green, David W
,
Ivanoff, Lucinda
,
Lambert, Dennis M
Published in
Biochemistry (Easton)
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A Check on Rational Drug Design: Crystal Structure of a Complex of Human Immunodeficiency Virus Type 1 Protease with a Novel .gamma.-Turn Mimetic Inhibitor
by
Hoog, Susan S
,
Zhao, Baoguang
,
Winborne, Evon
,
Fisher, Seth
,
Green, David W
,
DesJarlais, Renee L
,
Newlander, Kenneth A
,
Callahan, James F
,
Abdel-Meguid, Sherin S
,
Moore, Michael L
,
Huffman, William F
Published in
Journal of medicinal chemistry
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Three-dimensional structure of a simian immunodeficiency virus protease/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 protease inhibit...
by
Zhao, Baoguang
,
Winborne, Evon
,
Minnich, Michael D.
,
Culp, Jeffrey S.
,
Debouck, Christine
,
Abdel-Meguid, Sherin S.
Published in
Biochemistry (Easton)
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Binding Interactions of Human Interleukin 5 with Its Receptor α Subunit
by
Kyung Johanson
,
Edward Appelbaum
,
Michael Doyle
,
Preston Hensley
,
Baoguang Zhao
,
Sherin S. Abdel-Meguid
,
Peter Young
,
Richard Cook
,
Steven Carr
,
Rosalie Matico
,
Donna Cusimano
,
Edward Dul
,
Monica Angelichio
,
Ian Brooks
,
Evon Winborne
,
Peter McDonnell
,
Thomas Morton
,
Donald Bennett
,
Theodore Sokoloski
,
Dean McNulty
,
Martin Rosenberg
,
Irwin Chaiken
Published in
The Journal of biological chemistry
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Binding Interactions of Human Interleukin 5 with Its Receptor α Subunit
by
Johanson, Kyung
,
Appelbaum, Edward
,
Doyle, Michael
,
Hensley, Preston
,
Zhao, Baoguang
,
Abdel-Meguid, Sherin S.
,
Young, Peter
,
Cook, Richard
,
Carr, Steven
,
Matico, Rosalie
,
Cusimano, Donna
,
Dul, Edward
,
Angelichio, Monica
,
Brooks, Ian
,
Winborne, Evon
,
McDonnell, Peter
,
Morton, Thomas
,
Bennett, Donald
,
Sokoloski, Theodore
,
McNulty, Dean
,
Rosenberg, Martin
,
Chaiken, Irwin
Published in
The Journal of biological chemistry
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