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Diarylheptanoid 35d overcomes EGFR TKI resistance by inducing hsp70-mediated lysosomal degradation of EGFR in EGFR-mutant lung adenocarcinoma
by
Hong, Xuan
,
Hsieh, Min-Tsang
,
Tseng, Tzu-Yu
,
Lin, Hui-Yi
,
Chang, Hung-Chih
,
Yau, Sir-Theng
,
Cheng, Wei-Chung
,
Ke, Baozhen
,
Liao, Hsiao-Hui
,
Wu, Chih-Ying
,
Liu, An-An
,
Wu, Meei-Maan
,
Huang, Kuo-Yen
,
Yang, Pan-Chyr
,
Kuo, Sheng-Chu
,
Hung, Mien-Chie
,
Lee, Pei-Chih
Published in
The Journal of biological chemistry
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Journal Of Biological Chemistry/The Journal Of Biological Chemistry
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Adenocarcinoma Of Lung - Drug Therapy
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Adenocarcinoma Of Lung - Genetics
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Animals
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Biochemistry & Molecular Biology
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Cell Line, Tumor
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Diarylheptanoids - Pharmacology
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Drug Resistance, Neoplasm
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Egfr
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Egfr Mutation
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Erbb Receptors - Metabolism
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Humans
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Life Sciences & Biomedicine
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Lung Adenocarcinoma
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Lung Cancer
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Lung Neoplasms - Drug Therapy
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Lysosomes - Metabolism
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