Active Site and Laminarin Binding in Glycoside Hydrolase Family 55 by Bianchetti, Christopher M., Takasuka, Taichi E., Deutsch, Sam, Udell, Hannah S., Yik, Eric J., Bergeman, Lai F., Fox, Brian G.

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Engineering polymerases for applications in synthetic biology by Nikoomanzar, Ali, Chim, Nicholas, Yik, Eric J., Chaput, John C.

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P(V) Reagents for the Scalable Synthesis of Natural and Modified Nucleoside Triphosphates by Liao, Jen-Yu, Bala, Saikat, Ngor, Arlene K, Yik, Eric J, Chaput, John C

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Functional Comparison of Laboratory-Evolved XNA Polymerases for Synthetic Biology by Medina, Esau, Yik, Eric J, Herdewijn, Piet, Chaput, John C

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Programmed Allelic Mutagenesis of a DNA Polymerase with Single Amino Acid Resolution by Nikoomanzar, Ali, Vallejo, Derek, Yik, Eric J, Chaput, John C

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Synthesis and polymerase recognition of a pyrrolocytidine TNA triphosphate by Mei, Hui, Wang, Yajun, Yik, Eric J., Chaput, John C.

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Evolution of Functionally Enhanced α‑l‑Threofuranosyl Nucleic Acid Aptamers by McCloskey, Cailen M, Li, Qingfeng, Yik, Eric J, Chim, Nicholas, Ngor, Arlene K, Medina, Esau, Grubisic, Ivan, Co Ting Keh, Lance, Poplin, Ryan, Chaput, John C

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Direct Visualization of the Binding of Transforming Growth Factor Beta 1 with Cartilage Oligomeric Matrix Protein via High-Resolution Atomic Force Microscopy by Tran, Victoria, Karsai, Arpad, Fong, Michael C, Cai, Weiliang, Fraley, J. Gabriel, Yik, Jasper H.N, Klineberg, Eric, Haudenschild, Dominik R, Liu, Gang-yu

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Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals by Whiffin, Nicola, Karczewski, Konrad J., Zhang, Xiaolei, Chothani, Sonia, Smith, Miriam J., Evans, D. Gareth, Roberts, Angharad M., Quaife, Nicholas M., Schafer, Sebastian, Rackham, Owen, Alföldi, Jessica, O’Donnell-Luria, Anne H., Francioli, Laurent C., Cook, Stuart A., Barton, Paul J. R., MacArthur, Daniel G., Ware, James S.

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Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania by Band, Gavin, Le, Quang Si, Clarke, Geraldine M., Kivinen, Katja, Hubbart, Christina, Jeffreys, Anna E., Rowlands, Kate, Leffler, Ellen M., Jallow, Muminatou, Conway, David J., Sisay-Joof, Fatoumatta, Sirugo, Giorgio, d’Alessandro, Umberto, Toure, Ousmane B., Thera, Mahamadou A., Konate, Salimata, Sissoko, Sibiri, Mangano, Valentina D., Bougouma, Edith C., Sirima, Sodiomon B., Amenga-Etego, Lucas N., Ghansah, Anita K., Hodgson, Abraham V. O., Wilson, Michael D., Enimil, Anthony, Ansong, Daniel, Evans, Jennifer, Ademola, Subulade A., Apinjoh, Tobias O., Ndila, Carolyne M., Manjurano, Alphaxard, Drakeley, Chris, Reyburn, Hugh, Phu, Nguyen Hoan, Quyen, Nguyen Thi Ngoc, Thai, Cao Quang, Hien, Tran Tinh, Teo, Yik Ying, Manning, Laurens, Laman, Moses, Michon, Pascal, Karunajeewa, Harin, Siba, Peter, Allen, Steve, Allen, Angela, Bahlo, Melanie, Davis, Timothy M. E., Simpson, Victoria, Shelton, Jennifer, Spencer, Chris C. A., Busby, George B. J., Kerasidou, Angeliki, Drury, Eleanor, Stalker, Jim, Dilthey, Alexander, Mentzer, Alexander J., McVean, Gil, Bojang, Kalifa A., Doumbo, Ogobara, Modiano, David, Koram, Kwadwo A., Agbenyega, Tsiri, Amodu, Olukemi K., Achidi, Eric, Williams, Thomas N., Marsh, Kevin, Riley, Eleanor M., Molyneux, Malcolm, Taylor, Terrie, Dunstan, Sarah J., Farrar, Jeremy, Mueller, Ivo, Rockett, Kirk A., Kwiatkowski, Dominic P.

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Genome-wide association study identifies three novel loci for type 2 diabetes by Hara, Kazuo, Fujita, Hayato, Johnson, Todd A, Yamauchi, Toshimasa, Yasuda, Kazuki, Horikoshi, Momoko, Peng, Chen, Hu, Cheng, Ma, Ronald C W, Imamura, Minako, Iwata, Minoru, Tsunoda, Tatsuhiko, Morizono, Takashi, Shojima, Nobuhiro, So, Wing Yee, Leung, Ting Fan, Kwan, Patrick, Zhang, Rong, Wang, Jie, Yu, Weihui, Maegawa, Hiroshi, Hirose, Hiroshi, Kaku, Kohei, Ito, Chikako, Watada, Hirotaka, Tanaka, Yasushi, Tobe, Kazuyuki, Kashiwagi, Atsunori, Kawamori, Ryuzo, Jia, Weiping, Chan, Juliana C N, Teo, Yik Ying, Shyong, Tai E, Kamatani, Naoyuki, Kubo, Michiaki, Maeda, Shiro, Kadowaki, Takashi

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Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations by Fox, Ervin, Edwards, Todd L., Nalls, Michael A., Tayo, Bamidele O., Adeyemo, Adebawole, Young, J. Hunter, Duan, Qing, Chen, Fang, Li, Yun, Fornage, Myriam, Keene, Keith L., Andrews, Jeanette S., Smith, Jennifer A., Faul, Jessica D., Liu, Yu, Murray, Sarah S., Musani, Solomon K., Srinivasan, Sathanur, Velez Edwards, Digna R., Wang, Heming, Bovet, Pascal, Bochud, Murielle, Broeckel, Ulrich, Burnier, Michel, Chasman, Daniel I., Ehret, Georg, Chen, Wei-Min, Chen, Wei, Dreisbach, Albert W., Evans, Michele K., Guo, Xiuqing, Garcia, Melissa E., Jensen, Rich, Lettre, Guillaume, Lotay, Vaneet, Martin, Lisa W., Moore, Jason H., Morrison, Alanna C., Mosley, Thomas H., Penman, Alan, Polak, Joseph F., Ridker, Paul M., Salako, Babatunde, Singleton, Andrew B., Shriner, Daniel, Taylor, Kent D., Wiggins, Kerri, Williams, Scott M., Yanek, Lisa R., Zonderman, Alan B., Becker, Diane M., Berenson, Gerald, Boerwinkle, Eric, Bottinger, Erwin, Nyberg, Fredrik, Heiss, Gerardo, Howard, Virginia J., Liu, Kiang, Liu, Yongmei, Loos, Ruth, Snyder, Michael, Go, Min Jin, Kim, Young Jin, Lee, Jong-Young, Jeon, Jae-Pil, Han, Bok-Ghee, Cho, Yoon Shin, Tay, Wan Ting, Ong, Rick Twee Hee, Seielstad, Mark, Aung, Tin, Wong, Tien Yin, Tai, E. Shyong, Chang, Li-ching, Wu, Jer-Yuarn, Kelly, Tanika N., Hixson, James E., Sung, Yun Ju, Kato, Norihiro, Takeuchi, Fumihiko, Sugiyama, Takao, Zhang, Yi, Huang, Wei, Zhou, Xueya, Jin, Li, Zhu, Dingliang, Schork, Nicholas J., Weir, David R., Harris, Tamara, Hunt, Steven C., Arnett, Donna, Redline, Susan, Cooper, Richard S., Risch, Neil J., Rotter, Jerome I., Chakravarti, Aravinda, Reiner, Alex P., Levy, Daniel, Keating, Brendan J., Zhu, Xiaofeng

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Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia by Simino, Jeannette, Shi, Gang, Bis, Joshua C., Chasman, Daniel I., Ehret, Georg B., Guo, Xiuqing, Sijbrands, Eric, Smith, Albert V., Verwoert, Germaine C., Bragg-Gresham, Jennifer L., Cadby, Gemma, Chen, Peng, Cheng, Ching-Yu, Corre, Tanguy, de Boer, Rudolf A., Goel, Anuj, Johnson, Toby, Khor, Chiea-Chuen, Alizadeh, Behrooz Z., de Boer, Rudolf A., Boezen, H. Marike, Bruinenberg, Marcel, Franke, Lude, van der Harst, Pim, van der Klauw, Melanie M., Navis, Gerjan, Ormel, Johan, Postma, Dirkje S., Rosmalen, Judith G.M., Slaets, Joris P., Snieder, Harold, Stolk, Ronald P., Wolffenbuttel, Bruce H.R., Lluís-Ganella, Carla, Lyytikäinen, Leo-Pekka, Nolte, Ilja M., Sõber, Siim, van der Most, Peter J., Verweij, Niek, Amin, Najaf, Boerwinkle, Eric, Dehghan, Abbas, Eiriksdottir, Gudny, Elosua, Roberto, Franco, Oscar H., Gieger, Christian, Hofman, Albert, James, Alan L., Johnson, Andrew D., Kähönen, Mika, Khaw, Kay-Tee, Kutalik, Zoltan, Larson, Martin G., Launer, Lenore J., Li, Guo, Liu, Kiang, Morrison, Alanna C., Navis, Gerjan, Ong, Rick Twee-Hee, Papanicolau, George J., Penninx, Brenda W., Psaty, Bruce M., Raitakari, Olli T., Rivadeneira, Fernando, Rose, Lynda M., Sanna, Serena, Scott, Robert A., Siscovick, David S., Stolk, Ronald P., Vaidya, Dhananjay, van der Klauw, Melanie M., Vasan, Ramachandran S., Vithana, Eranga Nishanthie, Völker, Uwe, Watkins, Hugh, Young, Terri L., Aung, Tin, Bochud, Murielle, Farrall, Martin, Hartman, Catharina A., Laan, Maris, Lakatta, Edward G., Lehtimäki, Terho, Loos, Ruth J.F., Meneton, Pierre, Palmer, Lyle J., Rettig, Rainer, Snieder, Harold, Tai, E. Shyong, van der Harst, Pim, Wareham, Nicholas J., Wijmenga, Cisca, Wong, Tien Yin, Fornage, Myriam, Gudnason, Vilmundur, Levy, Daniel, Palmas, Walter, van Duijn, Cornelia M., Witteman, Jacqueline C.M., Rao, Dabeeru C.

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Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes by Dornbos, Peter, Chaffin, Mark D., Liu, Dajiang J., Wang, Minxian, Park, Joseph, Aguilar-Salinas, Carlos A., Arnett, Donna K., Barajas-Olmos, Francisco, Barzilai, Nir, Bielak, Lawrence F., Bis, Joshua C., Blangero, John, Boerwinkle, Eric, Bottinger, Erwin, Brody, Jennifer A., Broome, Jai G., Burtt, Noël P., Cade, Brian E., Chang, Yi-Cheng, Chen, Yii-Der I., Choi, Won Jung, Contreras-Cubas, Cecilia, Curran, Joanne E., de Vries, Paul S., DeFronzo, Ralph A., Doddapaneni, Harsha, Duggirala, Ravindranath, Dutcher, Susan K., Emery, Leslie S., Freedman, Barry I., García-Ortiz, Humberto, Gibbs, Richard A., Glaser, Benjamin, Gonzalez, Clicerio, Gonzalez-Villalpando, Maria Elena, Graff, Mariaelisa, Grarup, Niels, Gupta, Namrata, Hansen, Torben, Hung, Yi-Jen, Hwang, Mi Yeong, Irvin, Marguerite R., Kang, Hyun Min, Kardia, Sharon L.R., Kelly, Tanika, Khan, Alyna T., Kim, Bong-Jo, Kim, Young Jin, Lange, Leslie A., Lee, Juyoung, Lee, Seonwook, Lehman, Donna M., Linneberg, Allan, Liu, Jianjun, Lyssenko, Valeriya, Ma, Ronald C.W., Martínez-Hernández, Angélica, Mathias, Rasika A., Meigs, James B., Meitinger, Thomas, Metcalf, Ginger A., Mi, Xuenan, Mohlke, Karen L., Montasser, May E., Moon, Jee-Young, Morrison, Alanna C., Muzny, Donna M., Nelson, Sarah C., Nilsson, Peter M., O’Connell, Jeffrey R., Palmer, Nicholette D., Park, Cheol Joo, Peralta, Juan M., Peyser, Patricia A., Preuss, Michael, Qi, Qibin, Rao, D.C., Reiner, Alexander P., Rich, Stephen S., Samani, Nilesh, Schurmann, Claudia, Seo, Daekwan, Seo, Jeong-Sun, Sim, Xueling, Sladek, Rob, So, Wing Yee, Stilp, Adrienne M., Taylor, Kent D., Teo, Yik Ying, Tsai, Michael Y., Vasan, Ramachandran S., Watkins, Hugh, Weeks, Daniel E., Wilson, James G., Yanek, Lisa R., Rader, Daniel J., Rotter, Jerome I., McCarthy, Mark I., Flannick, Jason A., Khera, Amit V.

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Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis by Holliday, Elizabeth G, Smith, Albert V, Cornes, Belinda K, Buitendijk, Gabriëlle H S, Jensen, Richard A, Sim, Xueling, Aspelund, Thor, Aung, Tin, Baird, Paul N, Boerwinkle, Eric, Cheng, Ching Yu, van Duijn, Cornelia M, Eiriksdottir, Gudny, Gudnason, Vilmundur, Harris, Tamara, Hewitt, Alex W, Inouye, Michael, Jonasson, Fridbert, Klein, Barbara E K, Launer, Lenore, Li, Xiaohui, Liew, Gerald, Lumley, Thomas, McElduff, Patrick, McKnight, Barbara, Mitchell, Paul, Psaty, Bruce M, Rochtchina, Elena, Rotter, Jerome I, Scott, Rodney J, Tay, Wanting, Taylor, Kent, Teo, Yik Ying, Uitterlinden, André G, Viswanathan, Ananth, Xie, Sophia, Vingerling, Johannes R, Klaver, Caroline C W, Tai, E Shyong, Siscovick, David, Klein, Ronald, Cotch, Mary Frances, Wong, Tien Y, Attia, John, Wang, Jie Jin

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Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans by Karczewski, Konrad J., Francioli, Laurent C., Tiao, Grace, Cummings, Beryl B., Alföldi, Jessica, Wang, Qingbo, Collins, Ryan L., Laricchia, Kristen M., Ganna, Andrea, Birnbaum, Daniel P., Gauthier, Laura D., Brand, Harrison, Solomonson, Matthew, Watts, Nicholas A., Rhodes, Daniel, Singer-Berk, Moriel, England, Eleina M., Seaby, Eleanor G., Kosmicki, Jack A., Walters, Raymond K., Tashman, Katherine, Farjoun, Yossi, Banks, Eric, Poterba, Timothy, Wang, Arcturus, Seed, Cotton, Whiffin, Nicola, Chong, Jessica X., Samocha, Kaitlin E., Pierce-Hoffman, Emma, Zappala, Zachary, O’Donnell-Luria, Anne H., Minikel, Eric Vallabh, Weisburd, Ben, Lek, Monkol, Ware, James S., Vittal, Christopher, Armean, Irina M., Bergelson, Louis, Cibulskis, Kristian, Connolly, Kristen M., Covarrubias, Miguel, Donnelly, Stacey, Ferriera, Steven, Gabriel, Stacey, Gentry, Jeff, Gupta, Namrata, Jeandet, Thibault, Kaplan, Diane, Llanwarne, Christopher, Munshi, Ruchi, Novod, Sam, Petrillo, Nikelle, Roazen, David, Ruano-Rubio, Valentin, Saltzman, Andrea, Schleicher, Molly, Soto, Jose, Tibbetts, Kathleen, Tolonen, Charlotte, Wade, Gordon, Talkowski, Michael E., Neale, Benjamin M., Daly, Mark J., MacArthur, Daniel G.

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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls by Mercader, Josep M., Udler, Miriam S., Mahajan, Anubha, Caulkins, Lizz, Barajas-Olmos, Francisco, Blackwell, Thomas W., Boerwinkle, Eric, Brody, Jennifer A., Chen, Siying, Contreras-Cubas, Cecilia, Córdova, Emilio, Correa, Adolfo, Cortes, Maria, Dolan, Lawrence, Drews, Kimberly L., Gabriel, Stacey, Garay-Sevilla, Maria Eugenia, García-Ortiz, Humberto, Gross, Myron, Heard-Costa, Nancy L., Jackson, Anne U., Jørgensen, Marit E., Kang, Hyun Min, Kim, Bong-Jo, Lyssenko, Valeriya, Manning, Alisa K., Marcketta, Anthony, Martínez-Hernández, Angélica, Matsuo, Karen, Mayer-Davis, Elizabeth, Mohlke, Karen L., Morrison, Alanna C., Ndungu, Anne, Ng, Maggie C. Y., O’Dushlaine, Colm, Payne, Anthony J., Pihoker, Catherine, Preuss, Michael, Psaty, Bruce M., Reiner, Alexander P., Robertson, Neil R., Santoro, Nicola, Schurmann, Claudia, So, Wing Yee, Soberón, Xavier, Thameem, Farook, Tomlinson, Brian, van Dam, Rob M., Vujkovic, Marijana, Witte, Daniel R., Barzilai, Nir, Bonnycastle, Lori L., Bowden, Donald W., Chambers, John C., Cheng, Ching-Yu, de Vries, Paul S., Glaser, Benjamin, Groop, Leif, Kooner, Jaspal Singh, Kwak, Soo Heon, Lehman, Donna M., Spector, Timothy D., Tai, E. Shyong, Tuomilehto, Jaakko, Wilson, James G., Burke, Brian, Carey, David J., Chan, Juliana C. N., Dupuis, Josée, Frossard, Philippe, Heckbert, Susan R., Hwang, Mi Yeong, Kim, Young Jin, Kirchner, H. Lester, Lee, Jong-Young, Lee, Juyoung, Loos, Ruth J. F., Ma, Ronald C. W., O’Donnell, Christopher J., Park, Kyong Soo, Rasheed, Asif, Saleheen, Danish, Sim, Xueling, Hanis, Craig L., Orozco, Lorena, Dewey, Frederick E., Baras, Aris, Gieger, Christian, Meitinger, Thomas, Strauch, Konstantin, Lange, Leslie, Hansen, Torben, Pedersen, Oluf, Dabelea, Dana, Bell, Graeme I., Sladek, Rob, Rich, Steve S., Rotter, Jerome I., Altshuler, David, Boehnke, Michael

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Author Correction: Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals by Whiffin, Nicola, Karczewski, Konrad J., Zhang, Xiaolei, Chothani, Sonia, Smith, Miriam J., Evans, D. Gareth, Roberts, Angharad M., Quaife, Nicholas M., Schafer, Sebastian, Rackham, Owen, Alföldi, Jessica, O’Donnell-Luria, Anne H., Francioli, Laurent C., Cook, Stuart A., Barton, Paul J. R., MacArthur, Daniel G., Ware, James S.

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Author Correction: Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes by Wang, Qingbo, Pierce-Hoffman, Emma, Cummings, Beryl B., Alföldi, Jessica, Francioli, Laurent C., Gauthier, Laura D., Hill, Andrew J., O’Donnell-Luria, Anne H., Karczewski, Konrad J., MacArthur, Daniel G.

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Vitamin D deficiency exacerbates UV/endorphin and opioid addiction by Kemény, Lajos V, Robinson, Kathleen C, Hermann, Andrea L, Walker, Deena M, Regan, Susan, Yew, Yik Weng, Lai, Yi Chun, Theodosakis, Nicholas, Rivera, Phillip D, Ding, Weihua, Yang, Liuyue, Beyer, Tobias, Loh, Yong-Hwee E, Lo, Jennifer A, van der Sande, Anita A J, Sarnie, William, Kotler, David, Hsiao, Jennifer J, Su, Mack Y, Kato, Shinichiro, Kotler, Joseph, Bilbo, Staci D, Chopra, Vanita, Salomon, Matthew P, Shen, Shiqian, Hoon, Dave S B, Asgari, Maryam M, Wakeman, Sarah E, Nestler, Eric J, Fisher, David E

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