Imaging biomarkers in neurodegeneration: current and future practices by Young, Peter N E, Estarellas, Mar, Coomans, Emma, Srikrishna, Meera, Beaumont, Helen, Maass, Anne, Venkataraman, Ashwin V, Lissaman, Rikki, Jiménez, Daniel, Betts, Matthew J, McGlinchey, Eimear, Berron, David, O'Connor, Antoinette, Fox, Nick C, Pereira, Joana B, Jagust, William, Carter, Stephen F, Paterson, Ross W, Schöll, Michael

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Relevance of biomarkers across different neurodegenerative by Ehrenberg, Alexander J, Khatun, Ayesha, Coomans, Emma, Betts, Matthew J, Capraro, Federica, Thijssen, Elisabeth H, Senkevich, Konstantin, Bharucha, Tehmina, Jafarpour, Mehrsa, Young, Peter N. E, Jagust, William, Carter, Stephen F, Lashley, Tammaryn, Grinberg, Lea T, Pereira, Joana B, Mattsson-Carlgren, Niklas, Ashton, Nicholas J, Hanrieder, Jörg, Zetterberg, Henrik, Schöll, Michael, Paterson, Ross W

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Correction to: Relevance of biomarkers across different neurodegenerative diseases by Ehrenberg, Alexander J, Khatun, Ayesha, Coomans, Emma, Betts, Matthew J, Capraro, Federica, Thijssen, Elisabeth H, Senkevich, Konstantin, Bharucha, Tehmina, Jafarpour, Mehrsa, Young, Peter N. E, Jagust, William, Carter, Stephen F, Lashley, Tammaryn, Grinberg, Lea T, Pereira, Joana B, Mattsson-Carlgren, Niklas, Ashton, Nicholas J, Hanrieder, Jörg, Zetterberg, Henrik, Schöll, Michael, Paterson, Ross W

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Relevance of biomarkers across different neurodegenerative diseases by Ehrenberg, Alexander J, Khatun, Ayesha, Coomans, Emma, Betts, Matthew J, Capraro, Federica, Thijssen, Elisabeth H, Senkevich, Konstantin, Bharucha, Tehmina, Jafarpour, Mehrsa, Young, Peter N E, Jagust, William, Carter, Stephen F, Lashley, Tammaryn, Grinberg, Lea T, Pereira, Joana B, Mattsson-Carlgren, Niklas, Ashton, Nicholas J, Hanrieder, Jörg, Zetterberg, Henrik, Schöll, Michael, Paterson, Ross W

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Impact of simulated reduced injected dose on the assessment of amyloid PET scans by Young, Peter, Heeman, Fiona, Axelsson, Jan, Collij, Lyduine E., Hitzel, Anne, Sanaat, Amirhossein, Niñerola-Baizan, Aida, Perissinotti, Andrés, Lubberink, Mark, Frisoni, Giovanni B., Zaidi, Habib, Barkhof, Frederik, Farrar, Gill, Baker, Suzanne, Gispert, Juan Domingo, Garibotto, Valentina, Rieckmann, Anna, Schöll, Michael

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Image-derived input functions from dynamic O-15-water PET scans using penalised reconstruction by Young, Peter, Appel, Lieuwe, Tolf, Andreas, Kosmidis, Savvas, Burman, Joachim, Rieckmann, Anna, Schoell, Michael, Lubberink, Mark

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The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism by Murphy, James M., Czabotar, Peter E., Hildebrand, Joanne M., Lucet, Isabelle S., Zhang, Jian-Guo, Alvarez-Diaz, Silvia, Lewis, Rowena, Lalaoui, Najoua, Metcalf, Donald, Webb, Andrew I., Young, Samuel N., Varghese, Leila N., Tannahill, Gillian M., Hatchell, Esme C., Majewski, Ian J., Okamoto, Toru, Dobson, Renwick C.J., Hilton, Douglas J., Babon, Jeffrey J., Nicola, Nicos A., Strasser, Andreas, Silke, John, Alexander, Warren S.

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death by Hildebrand, Joanne M., Tanzer, Maria C., Lucet, Isabelle S., Young, Samuel N., Spall, Sukhdeep K., Sharma, Pooja, Pierotti, Catia, Garnier, Jean-Marc, Dobson, Renwick C.J., Webb, Andrew I., Tripaydonis, Anne, Babon, Jeffrey J., Mulcair, Mark D., Scanlon, Martin J., Alexander, Warren S., Wilks, Andrew F., Czabotar, Peter E., Lessene, Guillaume, Murphy, James M., Silke, John

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Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis by Garnish, Sarah E., Meng, Yanxiang, Koide, Akiko, Sandow, Jarrod J., Denbaum, Eric, Jacobsen, Annette V., Yeung, Wayland, Samson, Andre L., Horne, Christopher R., Fitzgibbon, Cheree, Young, Samuel N., Smith, Phoebe P. C., Webb, Andrew I., Petrie, Emma J., Hildebrand, Joanne M., Kannan, Natarajan, Czabotar, Peter E., Koide, Shohei, Murphy, James M.

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Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis by Meng, Yanxiang, Davies, Katherine A., Fitzgibbon, Cheree, Young, Samuel N., Garnish, Sarah E., Horne, Christopher R., Luo, Cindy, Garnier, Jean-Marc, Liang, Lung-Yu, Cowan, Angus D., Samson, Andre L., Lessene, Guillaume, Sandow, Jarrod J., Czabotar, Peter E., Murphy, James M.

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Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies by Petrie, Emma J., Birkinshaw, Richard W., Koide, Akiko, Denbaum, Eric, Hildebrand, Joanne M., Garnish, Sarah E., Davies, Katherine A., Sandow, Jarrod J., Samson, Andre L., Gavin, Xavier, Fitzgibbon, Cheree, Young, Samuel N., Hennessy, Patrick J., Smith, Phoebe P. C., Webb, Andrew I., Czabotar, Peter E., Koide, Shohei, Murphy, James M.

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Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic by Chin, Emily N, Yu, Chenguang, Vartabedian, Vincent F, Jia, Ying, Kumar, Manoj, Gamo, Ana M, Vernier, William, Ali, Sabrina H, Kissai, Mildred, Lazar, Daniel C, Nguyen, Nhan, Pereira, Laura E, Benish, Brent, Woods, Ashley K, Joseph, Sean B, Chu, Alan, Johnson, Kristen A, Sander, Philipp N, Martínez-Peña, Francisco, Hampton, Eric N, Young, Travis S, Wolan, Dennis W, Chatterjee, Arnab K, Schultz, Peter G, Petrassi, H Michael, Teijaro, John R, Lairson, Luke L

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Pioglitazone for secondary prevention after ischemic stroke and transient ischemic attack: Rationale and design of the Insulin Resistance Intervention after Stroke Trial by Viscoli, Catherine M., PhD, Brass, Lawrence M., MD, Carolei, Antonio, MD, Conwit, Robin, MD, Ford, Gary A., FRCP, Furie, Karen L., MD, MPH, Gorman, Mark, MD, Guarino, Peter D., PhD, Inzucchi, Silvio E., MD, Lovejoy, Anne M., PA-C, Parsons, Mark W., MD, Peduzzi, Peter N., PhD, Ringleb, Peter A., MD, Schwartz, Gregory G., MD, PhD, Spence, J. David, MD, Tanne, David, MD, Young, Lawrence H., MD, Kernan, Walter N., MD

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Landscape of somatic mutations in 560 breast cancer whole-genome sequences by Nik-Zainal, Serena, Davies, Helen, Staaf, Johan, Ramakrishna, Manasa, Glodzik, Dominik, Zou, Xueqing, Martincorena, Inigo, Alexandrov, Ludmil B., Martin, Sancha, Wedge, David C., Van Loo, Peter, Ju, Young Seok, Smid, Marcel, Brinkman, Arie B., Morganella, Sandro, Aure, Miriam R., Lingjærde, Ole Christian, Langerød, Anita, Ringnér, Markus, Ahn, Sung-Min, Boyault, Sandrine, Brock, Jane E., Broeks, Annegien, Butler, Adam, Desmedt, Christine, Dirix, Luc, Dronov, Serge, Fatima, Aquila, Foekens, John A., Gerstung, Moritz, Hooijer, Gerrit K. J., Jang, Se Jin, Jones, David R., Kim, Hyung-Yong, King, Tari A., Krishnamurthy, Savitri, Lee, Hee Jin, Lee, Jeong-Yeon, Li, Yilong, McLaren, Stuart, Menzies, Andrew, Mustonen, Ville, O’Meara, Sarah, Pauporté, Iris, Pivot, Xavier, Purdie, Colin A., Raine, Keiran, Ramakrishnan, Kamna, Rodríguez-González, F. Germán, Romieu, Gilles, Sieuwerts, Anieta M., Simpson, Peter T., Shepherd, Rebecca, Stebbings, Lucy, Stefansson, Olafur A., Teague, Jon, Tommasi, Stefania, Treilleux, Isabelle, Van den Eynden, Gert G., Vermeulen, Peter, Vincent-Salomon, Anne, Yates, Lucy, Caldas, Carlos, Veer, Laura van’t, Tutt, Andrew, Knappskog, Stian, Tan, Benita Kiat Tee, Jonkers, Jos, Borg, Åke, Ueno, Naoto T., Sotiriou, Christos, Viari, Alain, Futreal, P. Andrew, Campbell, Peter J., Span, Paul N., Van Laere, Steven, Lakhani, Sunil R., Eyfjord, Jorunn E., Thompson, Alastair M., Birney, Ewan, Stunnenberg, Hendrik G., van de Vijver, Marc J., Martens, John W. M., Børresen-Dale, Anne-Lise, Richardson, Andrea L., Kong, Gu, Thomas, Gilles, Stratton, Michael R.

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Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome by Lemas, Dominick J, Young, Bridget E, Baker, 2nd, Peter R, Tomczik, Angela C, Soderborg, Taylor K, Hernandez, Teri L, de la Houssaye, Becky A, Robertson, Charles E, Rudolph, Michael C, Ir, Diana, Patinkin, Zachary W, Krebs, Nancy F, Santorico, Stephanie A, Weir, Tiffany, Barbour, Linda A, Frank, Daniel N, Friedman, Jacob E

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Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues by Davies, Katherine A., Fitzgibbon, Cheree, Young, Samuel N., Garnish, Sarah E., Yeung, Wayland, Coursier, Diane, Birkinshaw, Richard W., Sandow, Jarrod J., Lehmann, Wil I. L., Liang, Lung-Yu, Lucet, Isabelle S., Chalmers, James D., Patrick, Wayne M., Kannan, Natarajan, Petrie, Emma J., Czabotar, Peter E., Murphy, James M.

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Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis by Petrie, Emma J., Sandow, Jarrod J., Jacobsen, Annette V., Smith, Brian J., Griffin, Michael D. W., Lucet, Isabelle S., Dai, Weiwen, Young, Samuel N., Tanzer, Maria C., Wardak, Ahmad, Liang, Lung-Yu, Cowan, Angus D., Hildebrand, Joanne M., Kersten, Wilhelmus J. A., Lessene, Guillaume, Silke, John, Czabotar, Peter E., Webb, Andrew I., Murphy, James M.

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The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis by Davies, Katherine A., Tanzer, Maria C., Griffin, Michael D. W., Mok, Yee Foong, Young, Samuel N., Qin, Rui, Petrie, Emma J., Czabotar, Peter E., Silke, John, Murphy, James M.

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Stroke genetics informs drug discovery and risk prediction across ancestries by Jürgenson, Tuuli, Namba, Shinichi, Posner, Daniel C., Kamanu, Frederick K., Koido, Masaru, He, Yunye, Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Parodi, Livia, Bae, Hee-Joon, Chong, Michael R., Tomppo, Liisa, Akinyemi, Rufus, Roshchupkin, Gennady V., Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Cárcel-Márquez, Jara, Nygaard, Marianne, Yonova-Doing, Ekaterina, Knol, Maria J., Lewis, Adam J., Judy, Renae L., Amouyel, Philippe, Bakker, Mark K., Bennett, David A., Bis, Joshua C., Bordes, Constance, Børte, Sigrid, Cain, Anael, Ridker, Paul M., Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W., de Cid, Rafael, Ferreira, Leslie E., He, Jing, Jeon, Christina E., Jern, Christina, Kamouchi, Masahiro, Keene, Keith L., Konuma, Takahiro, Kumar, Amit, Launer, Lenore J., Lee, Keon-Joo, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S., Meitinger, Thomas, Mitchell, Braxton D., Morisaki, Takayuki, O’Donnell, Martin J., Onland-Moret, N. Charlotte, Ovbiagele, Bruce, Peters, Annette, Rosand, Jonathan, Sabatine, Marc S., Sacco, Ralph L., Saleheen, Danish, Schmidt, Carsten O., Smith, Nicholas L., Sloane, Kelly L., Sutoh, Yoichi, Tiwari, Hemant K., Wennberg, Patrik, Wilson, Peter W. F., Yang, Qiong, Yoon, Kyungheon, Gieger, Christian, Ninomiya, Toshiharu, Grabe, Hans J., Jukema, J. Wouter, Kim, Young Jin, Chen, Pei-Hsin, Mayerhofer, Ernst, Ikram, Mohammad A., Worrall, Bradford B., Lathrop, G. Mark, Riaz, Moeen, Simonsick, Eleanor M., Kõrv, Janika, Zand, Ramin, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Ruigrok, Ynte M., Bastarache, Lisa, Damrauer, Scott M., Rotter, Jerome I., Niiranen, Teemu J., Walters, Robin G., Owolabi, Mayowa O., Huffman, Jennifer E., Kamatani, Yoichiro, Dichgans, Martin, Debette, Stephanie

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Identification of new genetic risk variants for type 2 diabetes by Shu, Xiao Ou, Long, Jirong, Cai, Qiuyin, Qi, Lu, Xiang, Yong-Bing, Cho, Yoon Shin, Tai, E Shyong, Li, Xiangyang, Lin, Xu, Chow, Wong-Ho, Go, Min Jin, Seielstad, Mark, Bao, Wei, Li, Huaixing, Cornelis, Marilyn C, Yu, Kai, Wen, Wanqing, Shi, Jiajun, Han, Bok-Ghee, Sim, Xue Ling, Liu, Liegang, Qi, Qibin, Kim, Hyung-Lae, Ng, Daniel P K, Lee, Jong-Young, Kim, Young Jin, Li, Chun, Gao, Yu-Tang, Zheng, Wei, Hu, Frank B

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