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mTORC2 inhibition by JR-AB2-011 improves IL-1β-induced inflammation, catabolic response, and apoptosis in human chondrocytes through IκB-α/NF-κB p65
by
Meryem Temiz-Resitoglu
,
Zainab Sabrie
,
Rukiye Nalan Tiftik
,
Taskın Kalkan
,
Ayca Aktas-Sukuroglu
,
Kafait U. Malik
,
Seyhan Sahan-Firat
Published in
Cellular and Molecular Biology
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Protection by selective mTORC2 inhibition of Zymosan-induced hypotension and systemic inflammation mediated via IKKα/IκB-α/NF-κB activation
by
Sabrie, Zainab
,
Temiz-Resitoglu, Meryem
,
Kalkan, Taskin
,
Kilic, Banu
,
Tunctan, Bahar
,
Malik, Kafait U.
,
Sahan-Firat, Seyhan
Published in
Prostaglandins & other lipid mediators
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Cellular And Molecular Biology
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Prostaglandins & Other Lipid Mediators
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Inflammation - Metabolism
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Inflammation - Pathology
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Mechanistic Target Of Rapamycin Complex 2 - Antagonists & Inhibitors
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Mechanistic Target Of Rapamycin Complex 2 - Metabolism
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Nf-Kappab Inhibitor Alpha - Metabolism
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Signal Transduction - Drug Effects
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Animals
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Apoptosis - Drug Effects
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Biochemistry & Molecular Biology
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Cell Biology
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Cells, Cultured
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Chondrocytes - Drug Effects
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Chondrocytes - Metabolism
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Humans
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Hypotension
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Hypotension - Chemically Induced
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Hypotension - Metabolism
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I-Kappa B Kinase - Antagonists & Inhibitors
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I-Kappa B Kinase - Metabolism
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Imidazoles
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