Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis by Lou, Yan, Han, Xiaochun, Kuglstatter, Andreas, Kondru, Rama K., Sweeney, Zachary K., Soth, Michael, McIntosh, Joel, Litman, Renee, Suh, Judy, Kocer, Buelent, Davis, Dana, Park, Jaehyeon, Frauchiger, Sandra, Dewdney, Nolan, Zecic, Hasim, Taygerly, Joshua P., Sarma, Keshab, Hong, Junbae, Hill, Ronald J., Gabriel, Tobias, Goldstein, David M., Owens, Timothy D.

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Platinum(II)-catalyzed intramolecular cyclization of alkynylbenzonitriles: synthesis of 1-alkoxyisoquinolines and isoquinolones by Li, Jim, Chen, Lijing, Chin, Elbert, Lui, Alfred S., Zecic, Hasim

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Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8 H -pyrido[2,3- d ]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(te... by Goldstein, David M., Soth, Michael, Gabriel, Tobias, Dewdney, Nolan, Kuglstatter, Andreas, Arzeno, Humberto, Chen, Jeffrey, Bingenheimer, William, Dalrymple, Stacie A., Dunn, James, Farrell, Robert, Frauchiger, Sandra, La Fargue, JoAnn, Ghate, Manjiri, Graves, Bradford, Hill, Ronald J., Li, Fujun, Litman, Renee, Loe, Brad, McIntosh, Joel, McWeeney, Daniel, Papp, Eva, Park, Jaehyeon, Reese, Harlan F., Roberts, Richard T., Rotstein, David, San Pablo, Bong, Sarma, Keshab, Stahl, Martin, Sung, Man-Ling, Suttman, Rebecca T., Sjogren, Eric B., Tan, Yunchou, Trejo, Alejandra, Welch, Mary, Weller, Paul, Wong, Brian R., Zecic, Hasim

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Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrah... by Goldstein, David M, Soth, Michael, Gabriel, Tobias, Dewdney, Nolan, Kuglstatter, Andreas, Arzeno, Humberto, Chen, Jeffrey, Bingenheimer, William, Dalrymple, Stacie A, Dunn, James, Farrell, Robert, Frauchiger, Sandra, La Fargue, JoAnn, Ghate, Manjiri, Graves, Bradford, Hill, Ronald J, Li, Fujun, Litman, Renee, Loe, Brad, McIntosh, Joel, McWeeney, Daniel, Papp, Eva, Park, Jaehyeon, Reese, Harlan F, Roberts, Richard T, Rotstein, David, San Pablo, Bong, Sarma, Keshab, Stahl, Martin, Sung, Man-Ling, Suttman, Rebecca T, Sjogren, Eric B, Tan, Yunchou, Trejo, Alejandra, Welch, Mary, Weller, Paul, Wong, Brian R, Zecic, Hasim

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3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: Design and development to a highly selective lead by Soth, Michael, Abbot, Sarah, Abubakari, Allassan, Arora, Nidhi, Arzeno, Humberto, Billedeau, Roland, Dewdney, Nolan, Durkin, Kieran, Frauchiger, Sandra, Ghate, Manjiri, Goldstein, David M., Hill, Ronald J., Kuglstatter, Andreas, Li, Fujun, Loe, Brad, McCaleb, Kristen, McIntosh, Joel, Papp, Eva, Park, Jaehyeon, Stahl, Martin, Sung, Man-Ling, Suttman, Rebecca, Swinney, David C., Weller, Paul, Wong, Brian, Zecic, Hasim, Gabriel, Tobias

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