A precision therapy against cancers driven by KIT/PDGFRA mutations by Evans, Erica K, Gardino, Alexandra K, Kim, Joseph L, Hodous, Brian L, Shutes, Adam, Davis, Alison, Zhu, Xing Julia, Schmidt-Kittler, Oleg, Wilson, Doug, Wilson, Kevin, DiPietro, Lucian, Zhang, Yulian, Brooijmans, Natasja, LaBranche, Timothy P, Wozniak, Agnieszka, Gebreyohannes, Yemarshet K, Schöffski, Patrick, Heinrich, Michael C, DeAngelo, Daniel J, Miller, Stephen, Wolf, Beni, Kohl, Nancy, Guzi, Timothy, Lydon, Nicholas, Boral, Andy, Lengauer, Christoph

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An ALK2 inhibitor, BLU-782, prevents heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva by Davis, Alison J, Brooijmans, Natasja, Brubaker, Jason D, Stevison, Faith, LaBranche, Timothy P, Albayya, Faris, Fleming, Paul, Hodous, Brian L, Kim, Joseph L, Kim, Sean, Lobbardi, Riadh, Palmer, Michael, Sheets, Michael P, Vassiliadis, John, Wang, Ruduan, Williams, Brett D, Wilson, Douglas, Xu, Lan, Zhu, Xing Julia, Bouchard, Keith, Hunter, Jeffrey W, Graul, Chris, Greenblatt, Elliot, Hussein, Amira, Lyon, Morgan, Russo, Joelle, Stewart, Rachel, Dorsch, Marion, Guzi, Timothy J, Kadambi, Vivek, Lengauer, Christoph, Garner, Andrew P

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Abstract 4290: The smoothened antagonist NVP-LDE225 targets stroma and cancer stem cells in primary human pancreatic tumor xenografts by Buonamici, Silvia, Ospina, Beatriz E., Zhu, Julia Xing, Yuan, Jing, Hsiao, Kathy, Vattay, Anthony, Li, Fang, Deeds, James, Ostrom, Lance, Monahan, John, Williams, Juliet, Kelleher, Joseph, Peukert, Stefan, Pan, Shifeng, Wu, Xu, Warmuth, Markus, Mosher, Rebecca, Yao, Yung-mae, Sellers, William R., Dorsch, Marion

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5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding by He, Yanlin, Cai, Xing, Liu, Hailan, Conde, Krisitine M., Xu, Pingwen, Li, Yongxiang, Wang, Chunmei, Yu, Meng, He, Yang, Liu, Hesong, Liang, Chen, Yang, Tingting, Yang, Yongjie, Yu, Kaifan, Wang, Julia, Zheng, Rong, Liu, Feng, Sun, Zheng, Heisler, Lora, Wu, Qi, Tong, Qingchun, Zhu, Canjun, Shu, Gang, Xu, Yong

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Bifunctional TGF-β trap/IL-15 protein complex elicits potent NK cell and CD8+ T cell immunity against solid tumors by Liu, Bai, Zhu, Xiaoyun, Kong, Lin, Wang, Meng, Spanoudis, Catherine, Chaturvedi, Pallavi, George, Varghese, Jiao, Jin-an, You, Lijing, Egan, Jack O., Echeverri, Christian, Gallo, Victor L., Xing, Jilan, Ravelo, Kristine, Prendes, Caitlin, Antolinez, Julian, Denissova, Julia, Muniz, Gabriela J., Jeng, Emily K., Rhode, Peter R., Wong, Hing C.

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