Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner by Elgendy, Mohamed, Ciro, Marco, Abdel-Aziz, Amal Kamal, Belmonte, Giuseppe, Zuffo, Roberto Dal, Mercurio, Ciro, Miracco, Clelia, Lanfrancone, Luisa, Foiani, Marco, Minucci, Saverio

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Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation by Ravasio, Roberto, Ceccacci, Elena, Nicosia, Luciano, Hosseini, Amir, Rossi, Pier Luigi, Barozzi, Iros, Fornasari, Lorenzo, Zuffo, Roberto Dal, Valente, Sergio, Fioravanti, Rossella, Mercurio, Ciro, Varasi, Mario, Mattevi, Andrea, Mai, Antonello, Pavesi, Giulio, Bonaldi, Tiziana, Minucci, Saverio

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Pathology tissue—chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples by Fanelli, Micro, Amatori, Stefano, Barozzi, Iros, Soncini, Matias, Zuffo, Roberto Dal, Bucci, Gabriele, Capra, Maria, Quarto, Micaela, Dellino, Gaetano Ivan, Mercurio, Ciro, Alcalay, Myriam, Viale, Giuseppe, Pelicci, Pier Giuseppe, Minucci, Saverio, Dawid, Igor B.

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Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent by Vianello, Paola, Botrugno, Oronza A, Cappa, Anna, Dal Zuffo, Roberto, Dessanti, Paola, Mai, Antonello, Marrocco, Biagina, Mattevi, Andrea, Meroni, Giuseppe, Minucci, Saverio, Stazi, Giulia, Thaler, Florian, Trifiró, Paolo, Valente, Sergio, Villa, Manuela, Varasi, Mario, Mercurio, Ciro

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Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models by Romussi, Alessia, Cappa, Anna, Vianello, Paola, Brambillasca, Silvia, Cera, Maria Rosaria, Dal Zuffo, Roberto, Fagà, Giovanni, Fattori, Raimondo, Moretti, Loris, Trifirò, Paolo, Villa, Manuela, Vultaggio, Stefania, Cecatiello, Valentina, Pasqualato, Sebastiano, Dondio, Giulio, So, Chi Wai Eric, Minucci, Saverio, Sartori, Luca, Varasi, Mario, Mercurio, Ciro

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Synthesis and biological characterization of spiro[2H-(1,3)-benzoxazine-2,4′-piperidine] based histone deacetylase inhibitors by Thaler, Florian, Varasi, Mario, Abate, Agnese, Carenzi, Giacomo, Colombo, Andrea, Bigogno, Chiara, Boggio, Roberto, Zuffo, Roberto Dal, Rapetti, Daniela, Resconi, Anna, Regalia, Nickolas, Vultaggio, Stefania, Dondio, Giulio, Gagliardi, Stefania, Minucci, Saverio, Mercurio, Ciro

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Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model by Trifirò, Paolo, Cappa, Anna, Brambillasca, Silvia, Botrugno, Oronza A, Cera, Maria Rosaria, Zuffo, Roberto Dal, Dessanti, Paola, Meroni, Giuseppe, Thaler, Florian, Villa, Manuela, Minucci, Saverio, Mercurio, Ciro, Varasi, Mario, Vianello, Paola

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Chiral Resolution and Pharmacological Characterization of the Enantiomers of the Hsp90 Inhibitor 2-Amino-7-[4-fluoro-2-(3-pyridyl)phenyl]-4-methyl-7,8-dihydro-6H-quinazolin-5-one O... by Amici, Raffaella, Bigogno, Chiara, Boggio, Roberto, Colombo, Andrea, Courtney, Stephen M., Dal Zuffo, Roberto, Dondio, Giulio, Fusar, Fulvia, Gagliardi, Stefania, Minucci, Saverio, Molteni, Marco, Montalbetti, Christian A. G. N., Mortoni, Annalisa, Varasi, Mario, Vultaggio, Stefania, Mercurio, Ciro

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Spiro[chromane-2,4′-piperidine]-Based Histone Deacetylase Inhibitors with Improved in vivo Activity by Thaler, Florian, Varasi, Mario, Carenzi, Giacomo, Colombo, Andrea, Abate, Agnese, Bigogno, Chiara, Boggio, Roberto, Carrara, Simone, Cataudella, Tiziana, Dal Zuffo, Roberto, Reali, Veronica, Vultaggio, Stefania, Dondio, Giulio, Gagliardi, Stefania, Minucci, Saverio, Mercurio, Ciro

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A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance by Santoro, Fabio, Botrugno, Oronza A., Dal Zuffo, Roberto, Pallavicini, Isabella, Matthews, Geoffrey M., Cluse, Leonie, Barozzi, Iros, Senese, Silvia, Fornasari, Lorenzo, Moretti, Simona, Altucci, Lucia, Pelicci, Pier Giuseppe, Chiocca, Susanna, Johnstone, Ricky W., Minucci, Saverio

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Discovery, Synthesis, and Pharmacological Evaluation of Spiropiperidine Hydroxamic Acid Based Derivatives as Structurally Novel Histone Deacetylase (HDAC) Inhibitors by Varasi, Mario, Thaler, Florian, Abate, Agnese, Bigogno, Chiara, Boggio, Roberto, Carenzi, Giacomo, Cataudella, Tiziana, Dal Zuffo, Roberto, Fulco, Maria Carmela, Rozio, Marco Giulio, Mai, Antonello, Dondio, Giulio, Minucci, Saverio, Mercurio, Ciro

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Chiral Resolution and Pharmacological Characterization of the Enantiomers of the Hsp90 Inhibitor 2‐Amino‐7‐[4‐fluoro‐2‐(3‐pyridyl)phenyl]‐4‐methyl‐7,8‐dihydro‐6 H ‐quinazolin‐5‐one... by Amici, Raffaella, Bigogno, Chiara, Boggio, Roberto, Colombo, Andrea, Courtney, Stephen M., Dal Zuffo, Roberto, Dondio, Giulio, Fusar, Fulvia, Gagliardi, Stefania, Minucci, Saverio, Molteni, Marco, Montalbetti, Christian A. G. N., Mortoni, Annalisa, Varasi, Mario, Vultaggio, Stefania, Mercurio, Ciro

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