Switch-task performance in rats is disturbed by 12 h of sleep deprivation but not by 12 h of sleep fragmentation by Leenaars, Cathalijn H C, Joosten, Ruud N J M A, Zwart, Allard, Sandberg, Hans, Ruimschotel, Emma, Hanegraaf, Maaike A J, Dematteis, Maurice, Feenstra, Matthijs G P, van Someren, Eus J W

Get full text

Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile by Barf, Tjeerd, Covey, Todd, Izumi, Raquel, van de Kar, Bas, Gulrajani, Michael, van Lith, Bart, van Hoek, Maaike, de Zwart, Edwin, Mittag, Diana, Demont, Dennis, Verkaik, Saskia, Krantz, Fanny, Pearson, Paul G, Ulrich, Roger, Kaptein, Allard

Get full text

Discovery and optimization of covalent EGFR T790M/L858R mutant inhibitors by Hoogenboom, Niels, Demont, Dennis, de Zwart, Edwin, Verkaik, Saskia, Emmelot, Maaike, van de Kar, Bas, Kaptein, Allard, Barf, Tjeerd

Get full text

Discovery of quinoline-based irreversible BTK inhibitors by de Bruin, Gerjan, Demont, Dennis, de Zwart, Edwin, Verkaik, Saskia, Hoogenboom, Niels, van de Kar, Bas, van Lith, Bart, Emmelot- van Hoek, Maaike, Gulrajani, Michael, Covey, Todd, Kaptein, Allard, Barf, Tjeerd

Get full text

Abstract 2596: ACP-196: a novel covalent Bruton's tyrosine kinase (Btk) inhibitor with improved selectivity and in vivo target coverage in chronic lymphocytic leukemia (CLL) patien... by Covey, Todd, Barf, Tjeerd, Gulrajani, Michael, Krantz, Fanny, van Lith, Bart, Bibikova, Elena, van de Kar, Bas, de Zwart, Edwin, Hamdy, Ahmed, Izumi, Raquel, Kaptein, Allard

Get full text

Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors by Kaptein, Allard, Oubrie, Arthur, Zwart, Edwin de, Hoogenboom, Niels, Wit, Joeri de, Kar, Bas van de, Hoek, Maaike van, Vogel, Gerard, Kimpe, Vera de, Schultz-Fademrecht, Carsten, Borsboom, Judith, Zeeland, Mario van, Versteegh, Judith, Kazemier, Bert, Roos, Jeroen de, Wijnands, Frank, Dulos, John, Jaeger, Martin, Leandro-Garcia, Paula, Barf, Tjeerd

Get full text

Novel ATP competitive MK2 inhibitors with potent biochemical and cell-based activity throughout the series by Oubrie, Arthur, Kaptein, Allard, de Zwart, Edwin, Hoogenboom, Niels, Goorden, Rianne, van de Kar, Bas, van Hoek, Maaike, de Kimpe, Vera, van der Heijden, Ruud, Borsboom, Judith, Kazemier, Bert, de Roos, Jeroen, Scheffers, Michiel, Lommerse, Jos, Schultz-Fademrecht, Carsten, Barf, Tjeerd

Get full text

Selection related to musculoskeletal complaints among employees by de Zwart, B C, Broersen, J P, van der Beek, A J, Frings-Dresen, M H, Van Dijk, F J

Get full text