Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice by Persaud, Avinash K., Bernier, Matthew C., Massey, Michael A., Agrawal, Shipra, Kaur, Tejinder, Nayak, Debasis, Xie, Zhiliang, Weadick, Brenna, Raj, Ruchika, Hill, Kasey, Abbott, Nicole, Joshi, Arnav, Anabtawi, Nadeen, Bryant, Claire, Somogyi, Arpad, Cruz-Monserrate, Zobeida, Amari, Foued, Coppola, Vincenzo, Sparreboom, Alex, Baker, Sharyn D., Unadkat, Jashvant D., Phelps, Mitch A., Govindarajan, Rajgopal

Get full text

Boosting the oral bioavailability of anticancer drugs through intentional drug–drug interactions by Eisenmann, Eric D., Talebi, Zahra, Sparreboom, Alex, Baker, Sharyn D.

Get full text

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms by Zhang, Haijiao, Savage, Samantha, Schultz, Anna Reister, Bottomly, Daniel, White, Libbey, Segerdell, Erik, Wilmot, Beth, McWeeney, Shannon K., Eide, Christopher A., Nechiporuk, Tamilla, Carlos, Amy, Henson, Rachel, Lin, Chenwei, Searles, Robert, Ho, Hoang, Lam, Yee Ling, Sweat, Richard, Follit, Courtney, Jain, Vinay, Lind, Evan, Borthakur, Gautam, Garcia-Manero, Guillermo, Ravandi, Farhad, Kantarjian, Hagop M., Cortes, Jorge, Collins, Robert, Buelow, Daelynn R., Baker, Sharyn D., Druker, Brian J., Tyner, Jeffrey W.

Get full text

In Memoriam Michelle A. Rudek (1972–2023) by Baker, Sharyn D., Figg, William D.

Get full text

Role of Oatp2b1 in Drug Absorption and Drug-Drug Interactions by Chen, Mingqing, Hu, Shuiying, Li, Yang, Gibson, Alice A., Fu, Qiang, Baker, Sharyn D., Sparreboom, Alex

Get full text

Differential Metabolism of Gefitinib and Erlotinib by Human Cytochrome P450 Enzymes by Li, Jing, Zhao, Ming, He, Ping, Hidalgo, Manuel, Baker, Sharyn D

Get full text

Crenolanib is active against models of drug-resistant FLT3-ITD−positive acute myeloid leukemia by Zimmerman, Eric I., Turner, David C., Buaboonnam, Jassada, Hu, Shuiying, Orwick, Shelley, Roberts, Michael S., Janke, Laura J., Ramachandran, Abhijit, Stewart, Clinton F., Inaba, Hiroto, Baker, Sharyn D.

Get full text

Determination and disposition of meta-iodobenzylguanidine in plasma and heart of transporter-deficient mice by UPLC-MS/MS by Talebi, Zahra, Jin, Yan, Baker, Sharyn D., Addison, Daniel, Sparreboom, Alex

Get full text

In memoriam Michelle A. Rudek (1972–2023) by Baker, Sharyn D., Figg, William D.

Get full text

Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide by Zimmerman, Eric I, Hu, Shuiying, Roberts, Justin L, Gibson, Alice A, Orwick, Shelley J, Li, Lie, Sparreboom, Alex, Baker, Sharyn D

Get full text

Targeting OCT3 attenuates doxorubicin-induced cardiac injury by Huang, Kevin M., Thomas, Megan Zavorka, Magdy, Tarek, Eisenmann, Eric D., Uddin, Muhammad Erfan, DiGiacomo, Duncan F., Pan, Alexander, Keiser, Markus, Otter, Marcus, Xia, Sherry H., Li, Yang, Jin, Yan, Fu, Qiang, Gibson, Alice A., Bonilla, Ingrid M., Carnes, Cynthia A., Corps, Kara N., Coppola, Vincenzo, Smith, Sakima A., Addison, Daniel, Nies, Anne T., Bundschuh, Ralf, Chen, Taosheng, Lustberg, Maryam B., Wang, Joanne, Oswald, Stefan, Campbell, Moray J., Yan, Pearlly S., Baker, Sharyn D., Hu, Shuiying, Burridge, Paul W., Sparreboom, Alex

Get full text

A phosphotyrosine switch regulates organic cation transporters by Sprowl, Jason A., Ong, Su Sien, Gibson, Alice A., Hu, Shuiying, Du, Guoqing, Lin, Wenwei, Li, Lie, Bharill, Shashank, Ness, Rachel A., Stecula, Adrian, Offer, Steven M., Diasio, Robert B., Nies, Anne T., Schwab, Matthias, Cavaletti, Guido, Schlatter, Eberhard, Ciarimboli, Giuliano, Schellens, Jan H. M., Isacoff, Ehud Y., Sali, Andrej, Chen, Taosheng, Baker, Sharyn D., Sparreboom, Alex, Pabla, Navjotsingh

Get full text

Panobinostat enhances cytarabine and daunorubicin sensitivities in AML cells through suppressing the expression of BRCA1, CHK1, and Rad51 by Xie, Chengzhi, Drenberg, Christina, Edwards, Holly, Caldwell, J Timothy, Chen, Wei, Inaba, Hiroto, Xu, Xuelian, Buck, Steven A, Taub, Jeffrey W, Baker, Sharyn D, Ge, Yubin

Get full text

Pharmacokinetic assessment of low dose decitabine in combination therapies: Development and validation of a sensitive UHPLC-MS/MS method for murine plasma analysis by Anabtawi, Nadeen, Drabison, Thomas, Jin, Yan, Eisenmann, Eric D., Sparreboom, Alex, Govindarajan, Rajgopal, Baker, Sharyn D., Ahmed, Eman

Get full text

Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b by Vasilyeva, Aksana, Durmus, Selvi, Li, Lie, Wagenaar, Els, Hu, Shuiying, Gibson, Alice A, Panetta, John C, Mani, Sridhar, Sparreboom, Alex, Baker, Sharyn D, Schinkel, Alfred H

Get full text

Determination of the endogenous OATP1B biomarkers glycochenodeoxycholate-3-sulfate and chenodeoxycholate-24-glucuronide in human and mouse plasma by a validated UHPLC-MS/MS method by Jin, Yan, Li, Yang, Eisenmann, Eric D., Figg, William D., Baker, Sharyn D., Sparreboom, Alex, Hu, Shuiying

Get full text

Itraconazole-Induced Increases in Gilteritinib Exposure Are Mediated by CYP3A and OATP1B by Garrison, Dominique A, Jin, Yan, Talebi, Zahra, Hu, Shuiying, Sparreboom, Alex, Baker, Sharyn D, Eisenmann, Eric D

Get full text

DNA methyltransferase inhibitor exposure–response: Challenges and opportunities by Kagan, Amanda B., Garrison, Dominique A., Anders, Nicole M., Webster, Jonathan A., Baker, Sharyn D., Yegnasubramanian, Srinivasan, Rudek, Michelle A.

Get full text

CREBBP mutations in relapsed acute lymphoblastic leukaemia by Mullighan, Charles G, Zhang, Jinghui, Kasper, Lawryn H, Lerach, Stephanie, Payne-Turner, Debbie, Phillips, Letha A, Heatley, Sue L, Holmfeldt, Linda, Collins-Underwood, J. Racquel, Ma, Jing, Buetow, Kenneth H, Pui, Ching-Hon, Baker, Sharyn D, Brindle, Paul K, Downing, James R

Get full text

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury by Kim, Ji Young, Bai, Yuntao, Jayne, Laura A., Hector, Ralph D., Persaud, Avinash K., Ong, Su Sien, Rojesh, Shreshtha, Raj, Radhika, Feng, Mei Ji He Ho, Chung, Sangwoon, Cianciolo, Rachel E., Christman, John W., Campbell, Moray J., Gardner, David S., Baker, Sharyn D., Sparreboom, Alex, Govindarajan, Rajgopal, Singh, Harpreet, Chen, Taosheng, Poi, Ming, Susztak, Katalin, Cobb, Stuart R., Pabla, Navjot Singh

Get full text