Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels by van Leeuwen, Elisabeth M., Karssen, Lennart C., Deelen, Joris, Isaacs, Aaron, Medina-Gomez, Carolina, Mbarek, Hamdi, Kanterakis, Alexandros, Trompet, Stella, Postmus, Iris, Verweij, Niek, van Enckevort, David J., Huffman, Jennifer E., White, Charles C., Feitosa, Mary F., Bartz, Traci M., Manichaikul, Ani, Joshi, Peter K., Peloso, Gina M., Deelen, Patrick, van Dijk, Freerk, Willemsen, Gonneke, de Geus, Eco J., Milaneschi, Yuri, Penninx, Brenda W.J.H., Francioli, Laurent C., Menelaou, Androniki, Pulit, Sara L., Rivadeneira, Fernando, Hofman, Albert, Oostra, Ben A., Franco, Oscar H., Leach, Irene Mateo, Beekman, Marian, de Craen, Anton J.M., Uh, Hae-Won, Trochet, Holly, Hocking, Lynne J., Porteous, David J., Sattar, Naveed, Packard, Chris J., Buckley, Brendan M., Brody, Jennifer A., Bis, Joshua C., Rotter, Jerome I., Mychaleckyj, Josyf C., Campbell, Harry, Duan, Qing, Lange, Leslie A., Wilson, James F., Hayward, Caroline, Polasek, Ozren, Vitart, Veronique, Rudan, Igor, Wright, Alan F., Rich, Stephen S., Psaty, Bruce M., Borecki, Ingrid B., Kearney, Patricia M., Stott, David J., Adrienne Cupples, L., Jukema, J. Wouter, van der Harst, Pim, Sijbrands, Eric J., Hottenga, Jouke-Jan, Uitterlinden, Andre G., Swertz, Morris A., van Ommen, Gert-Jan B., de Bakker, Paul I.W., Eline Slagboom, P., Boomsma, Dorret I., Wijmenga, Cisca, van Duijn, Cornelia M.

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The Genome of the Netherlands: design, and project goals by Boomsma, Dorret I, Wijmenga, Cisca, Slagboom, Eline P, Swertz, Morris A, Karssen, Lennart C, Abdellaoui, Abdel, Ye, Kai, Guryev, Victor, Vermaat, Martijn, van Dijk, Freerk, Francioli, Laurent C, Hottenga, Jouke Jan, Laros, Jeroen F J, Li, Qibin, Li, Yingrui, Cao, Hongzhi, Chen, Ruoyan, Du, Yuanping, Li, Ning, Cao, Sujie, van Setten, Jessica, Menelaou, Androniki, Pulit, Sara L, Hehir-Kwa, Jayne Y, Beekman, Marian, Elbers, Clara C, Byelas, Heorhiy, de Craen, Anton J M, Deelen, Patrick, Dijkstra, Martijn, den Dunnen, Johan T, de Knijff, Peter, Houwing-Duistermaat, Jeanine, Koval, Vyacheslav, Estrada, Karol, Hofman, Albert, Kanterakis, Alexandros, Enckevort, David van, Mai, Hailiang, Kattenberg, Mathijs, van Leeuwen, Elisabeth M, Neerincx, Pieter B T, Oostra, Ben, Rivadeneira, Fernanodo, Suchiman, Eka H D, Uitterlinden, Andre G, Willemsen, Gonneke, Wolffenbuttel, Bruce H, Wang, Jun, de Bakker, Paul I W, van Ommen, Gert-Jan, van Duijn, Cornelia M

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A high-quality human reference panel reveals the complexity and distribution of genomic structural variants by Hehir-Kwa, Jayne Y., Marschall, Tobias, Kloosterman, Wigard P., Francioli, Laurent C., Baaijens, Jasmijn A., Dijkstra, Louis J., Abdellaoui, Abdel, Koval, Vyacheslav, Thung, Djie Tjwan, Wardenaar, René, Renkens, Ivo, Coe, Bradley P., Deelen, Patrick, de Ligt, Joep, Lameijer, Eric-Wubbo, van Dijk, Freerk, Hormozdiari, Fereydoun, Uitterlinden, André G., van Duijn, Cornelia M., Eichler, Evan E., de Bakker, Paul I. W., Swertz, Morris A., Wijmenga, Cisca, van Ommen, Gert-Jan B., Slagboom, P. Eline, Boomsma, Dorret I., Schönhuth, Alexander, Ye, Kai, Guryev, Victor

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Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands' by Deelen, Patrick, Menelaou, Androniki, van Leeuwen, Elisabeth M, Kanterakis, Alexandros, van Dijk, Freerk, Medina-Gomez, Carolina, Francioli, Laurent C, Hottenga, Jouke Jan, Karssen, Lennart C, Estrada, Karol, Kreiner-Møller, Eskil, Rivadeneira, Fernando, van Setten, Jessica, Gutierrez-Achury, Javier, Westra, Harm-Jan, Franke, Lude, van Enckevort, David, Dijkstra, Martijn, Byelas, Heorhiy, van Duijn, Cornelia M, de Bakker, Paul I W, Wijmenga, Cisca, Swertz, Morris A

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Characteristics of de novo structural changes in the human genome by Kloosterman, Wigard P, Francioli, Laurent C, Hormozdiari, Fereydoun, Marschall, Tobias, Hehir-Kwa, Jayne Y, Abdellaoui, Abdel, Lameijer, Eric-Wubbo, Moed, Matthijs H, Koval, Vyacheslav, Renkens, Ivo, van Roosmalen, Markus J, Arp, Pascal, Karssen, Lennart C, Coe, Bradley P, Handsaker, Robert E, Suchiman, Eka D, Cuppen, Edwin, Thung, Djie Tjwan, McVey, Mitch, Wendl, Michael C, Uitterlinden, André, van Duijn, Cornelia M, Swertz, Morris A, Wijmenga, Cisca, van Ommen, GertJan B, Slagboom, P Eline, Boomsma, Dorret I, Schönhuth, Alexander, Eichler, Evan E, de Bakker, Paul I W, Ye, Kai, Guryev, Victor

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Negative selection in humans and fruit flies involves synergistic epistasis by Sohail, Mashaal, Vakhrusheva, Olga A., Sul, Jae Hoon, Pulit, Sara L., Francioli, Laurent C., van den Berg, Leonard H., Veldink, Jan H., de Bakker, Paul I. W., Bazykin, Georgii A., Kondrashov, Alexey S., Sunyaev, Shamil R.

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Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck by Li, Mingkun, Rothwell, Rebecca, Vermaat, Martijn, Wachsmuth, Manja, Schröder, Roland, Laros, Jeroen F J, van Oven, Mannis, de Bakker, Paul I W, Bovenberg, Jasper A, van Duijn, Cornelia M, van Ommen, Gert-Jan B, Slagboom, P Eline, Swertz, Morris A, Wijmenga, Cisca, Kayser, Manfred, Boomsma, Dorret I, Zöllner, Sebastian, de Knijff, Peter, Stoneking, Mark

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Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates by Palamara, Pier Francesco, Francioli, Laurent C., Wilton, Peter R., Genovese, Giulio, Gusev, Alexander, Finucane, Hilary K., Sankararaman, Sriram, Sunyaev, Shamil R., de Bakker, Paul I.W., Wakeley, John, Pe’er, Itsik, Price, Alkes L.

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WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene by Nersisyan, Lilit, Nikoghosyan, Maria, Arakelyan, Arsen

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Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency by Kiezun, Adam, Pulit, Sara L, Francioli, Laurent C, van Dijk, Freerk, Swertz, Morris, Boomsma, Dorret I, van Duijn, Cornelia M, Slagboom, P Eline, van Ommen, G J B, Wijmenga, Cisca, de Bakker, Paul I W, Sunyaev, Shamil R

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A framework for the detection of de novo mutations in family-based sequencing data by Francioli, Laurent C, Cretu-Stancu, Mircea, Garimella, Kiran V, Fromer, Menachem, Kloosterman, Wigard P, Samocha, Kaitlin E, Neale, Benjamin M, Daly, Mark J, Banks, Eric, DePristo, Mark A, de Bakker, Paul Iw

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Integration of EGA secure data access into Galaxy by Hoogstrate, Youri, Zhang, Chao, Senf, Alexander, Bijlard, Jochem, Hiltemann, Saskia, van Enckevort, David, Repo, Susanna, Heringa, Jaap, Jenster, Guido, J A Fijneman, Remond, Boiten, Jan-Willem, A Meijer, Gerrit, Stubbs, Andrew, Rambla, Jordi, Spalding, Dylan, Abeln, Sanne

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Systematically linking tranSMART, Galaxy and EGA for reusing human translational research data by Zhang, Chao, Bijlard, Jochem, Staiger, Christine, Scollen, Serena, van Enckevort, David, Hoogstrate, Youri, Senf, Alexander, Hiltemann, Saskia, Repo, Susanna, Pipping, Wibo, Bierkens, Mariska, Payralbe, Stefan, Stringer, Bas, Heringa, Jaap, Stubbs, Andrew, Bonino Da Silva Santos, Luiz Olavo, Belien, Jeroen, Weistra, Ward, Azevedo, Rita, van Bochove, Kees, Meijer, Gerrit, Boiten, Jan-Willem, Rambla, Jordi, Fijneman, Remond, Spalding, J Dylan, Abeln, Sanne

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