GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility by Judson, Matthew C., Wallace, Michael L., Sidorov, Michael S., Burette, Alain C., Gu, Bin, van Woerden, Geeske M., King, Ian F., Han, Ji Eun, Zylka, Mark J., Elgersma, Ype, Weinberg, Richard J., Philpot, Benjamin D.

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Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment by COCHAT, Pierre, HULTON, Sally-Anne, JAMIESON, Neville V, KEMPER, Markus J, MANDRILE, Giorgia, MARANGELLA, Martino, PICCA, Stefano, RUMSBY, Gill, SALIDO, Eduardo, STRAUB, Michael, WOERDEN, Christiaan S. Van, ACQUAVIVA, Cecile, DANPURE, Christopher J, DAUDON, Michel, DE MARCHI, Mario, FARGUE, Sonia, GROOTHOFF, Jaap, HARAMBAT, Jerome, HOPPE, Bernd

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HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1 by Omrani, A, van der Vaart, T, Mientjes, E, van Woerden, G M, Hojjati, M R, Li, K W, Gutmann, D H, Levelt, C N, Smit, A B, Silva, A J, Kushner, S A, Elgersma, Y

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RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity by Proietti Onori, Martina, Koene, Linda M. C, Schäfer, Carmen B, Nellist, Mark, de Brito van Velze, Marcel, Gao, Zhenyu, Elgersma, Ype, van Woerden, Geeske M

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Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability by Reijnders, M. R. F., Kousi, M., van Woerden, G. M., Klein, M., Bralten, J., Mancini, G. M. S., van Essen, T., Proietti-Onori, M., Smeets, E. E. J., van Gastel, M., Stegmann, A. P. A., Stevens, S. J. C., Lelieveld, S. H., Gilissen, C., Pfundt, R., Tan, P. L., Kleefstra, T., Franke, B., Elgersma, Y., Katsanis, N., Brunner, H. G.

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Adult Ube3a Gene Reinstatement Restores the Electrophysiological Deficits of Prefrontal Cortex Layer 5 Neurons in a Mouse Model of Angelman Syndrome by Rotaru, Diana C, van Woerden, Geeske M, Wallaard, Ilse, Elgersma, Ype

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Primary hyperoxaluria Type 1, a too often missed diagnosis and potentially treatable cause of end-stage renal disease in adults: results of the Dutch cohort by DER HOEVEN, S. M. Van, WOERDEN, C. S. Van, GROOTHOFF, J. W

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Intravenous immunoglobulin vs observation in childhood immune thrombocytopenia: a randomized controlled trial by Heitink-Pollé, Katja M.J., Uiterwaal, Cuno S.P.M., Porcelijn, Leendert, Tamminga, Rienk Y.J., Smiers, Frans J., van Woerden, Nicole L., Wesseling, Judit, Vidarsson, Gestur, Laarhoven, Annemieke G., de Haas, Masja, Bruin, Marrie C.A., for the TIKI Investigators

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Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries by Linschoten, M, Uijl, A, Schut, A, Jakob, C E M, Romão, L R, Bell, R M, McFarlane, E, Stecher, M, Zondag, A G M, van Iperen, E P A, Hermans-van Ast, W, Lea, N C, Schaap, J, Jewbali, L S, Smits, P C, Patel, R S, Aujayeb, A, van der Harst, P, Siebelink, H J, van Smeden, M, Williams, S, Pilgram, L, van Gilst, W H, Tieleman, R G, Williams, B, Asselbergs, F W, Al-Ali, A K, Al-Muhanna, F A, Al-Rubaish, A M, Al-Windy, N Y Y, Alkhalil, M, Almubarak, Y A, Alnafie, A N, Alshahrani, M, Alshehri, A M, Anning, C, Anthonio, R L, Badings, E A, Ball, C, van Beek, E A, ten Berg, J M, von Bergwelt-Baildon, M, Bianco, M, Blagova, O V, Bleijendaal, H, Bor, W L, Borgmann, S, van Boxem, A J M, van den Brink, F S, Bucciarelli-Ducci, C, van Bussel, B C T, Byrom-Goulthorp, R, Captur, G, Caputo, M, Charlotte, N, vom Dahl, J, Dark, P, De Sutter, J, Degenhardt, C, Delsing, C E, Dolff, S, Dorman, H G R, Drost, J T, Eberwein, L, Emans, M E, Er, A G, Ferreira, J B, Forner, M J, Friedrichs, A, Gabriel, L, Groenemeijer, B E, Groenendijk, A L, Grüner, B, Guggemos, W, Haerkens-Arends, H E, Hanses, F, Hedayat, B, Heigener, D, van der Heijden, D J, Hellou, E, Hellwig, K, Henkens, M T H M, Hermanides, R S, Hermans, W R M, van Hessen, M W J, Heymans, S R B, Hilt, A D, van der Horst, I C C, Hower, M, van Ierssel, S H, Isberner, N, Jensen, B, Kearney, M T, van Kesteren, H A M, Kielstein, J T, Kietselaer, B L J H, Kochanek, M, Kolk, M Z H, Koning, A M H, Kopylov, P Y

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CAMK2; four genes, one syndrome? Delineation of genotype–phenotype correlations by Cheung, Joshua S., van Woerden, Geeske M., Veenma, Danielle C.M.

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Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome by Avagliano Trezza, Rossella, Sonzogni, Monica, Bossuyt, Stijn N. V., Zampeta, F. Isabella, Punt, A. Mattijs, van den Berg, Marlene, Rotaru, Diana C., Koene, Linda M. C., Munshi, Shashini T., Stedehouder, Jeffrey, Kros, Johan M., Williams, Mark, Heussler, Helen, de Vrij, Femke M. S., Mientjes, Edwin J., van Woerden, Geeske M., Kushner, Steven A., Distel, Ben, Elgersma, Ype

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Ventricular tachyarrhythmia detection by implantable loop recording in patients with heart failure and preserved ejection fraction: the VIP‐HF study by Veldhuisen, Dirk J., Woerden, Gijs, Gorter, Thomas M., Empel, Vanessa P.M., Manintveld, Olivier C., Tieleman, Robert G., Maass, Alexander H., Vernooy, Kevin, Westenbrink, B. Daan, Gelder, Isabelle C., Rienstra, Michiel

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Dietary quality and bisphenols: trends in bisphenol A, F, and S exposure in relation to the Healthy Eating Index using representative data from the NHANES 2007–2016 by van Woerden, Irene, Payne-Sturges, Devon C, Whisner, Corrie M, Bruening, Meg

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Running in the FAMILY: understanding and predicting the intergenerational transmission of mental illness by van Houtum, Lisanne A. E. M., Baaré, William F. C., Beckmann, Christian F., Castro-Fornieles, Josefina, Cecil, Charlotte A. M., Dittrich, Juliane, Ebdrup, Bjørn H., Fegert, Jörg M., Havdahl, Alexandra, Hillegers, Manon H. J., Kalisch, Raffael, Kushner, Steven A., Mansuy, Isabelle M., Mežinska, Signe, Moreno, Carmen, Muetzel, Ryan L., Neumann, Alexander, Nordentoft, Merete, Pingault, Jean-Baptiste, Preisig, Martin, Raballo, Andrea, Saunders, John, Sprooten, Emma, Sugranyes, Gisela, Tiemeier, Henning, van Woerden, Geeske M., Vandeleur, Caroline L., van Haren, Neeltje E. M.

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Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes by Sonzogni, Monica, Hakonen, Johanna, Bernabé Kleijn, Mireia, Silva-Santos, Sara, Judson, Matthew C, Philpot, Benjamin D, van Woerden, Geeske M, Elgersma, Ype

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Case Report: Developmental Delay and Acute Neuropsychiatric Episodes Associated With a de novo Mutation in the CAMK2B Gene (c.328G>A p.Glu110Lys) by Dwyer, Bonnie K, Veenma, Danielle C M, Chang, Kiki, Schulman, Howard, Van Woerden, Geeske M

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Dissociation of locomotor and cerebellar deficits in a murine Angelman syndrome model by Bruinsma, Caroline F, Schonewille, Martijn, Gao, Zhenyu, Aronica, Eleonora M A, Judson, Matthew C, Philpot, Benjamin D, Hoebeek, Freek E, van Woerden, Geeske M, De Zeeuw, Chris I, Elgersma, Ype

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PSMC3 proteasome subunit variants are associated with neurodevelopmental delay and type I interferon production by Ebstein, Frédéric, Küry, Sébastien, Most, Victoria, Rosenfelt, Cory, Scott-Boyer, Marie-Pier, van Woerden, Geeske M, Besnard, Thomas, Papendorf, Jonas Johannes, Studencka-Turski, Maja, Wang, Tianyun, Hsieh, Tzung-Chien, Golnik, Richard, Baldridge, Dustin, Forster, Cara, de Konink, Charlotte, Teurlings, Selina M W, Vignard, Virginie, van Jaarsveld, Richard H, Ades, Lesley, Cogné, Benjamin, Mignot, Cyril, Deb, Wallid, Jongmans, Marjolijn C J, Cole, F Sessions, van den Boogaard, Marie-José H, Wambach, Jennifer A, Wegner, Daniel J, Yang, Sandra, Hannig, Vickie, Brault, Jennifer Ann, Zadeh, Neda, Bennetts, Bruce, Keren, Boris, Gélineau, Anne-Claire, Powis, Zöe, Towne, Meghan, Bachman, Kristine, Seeley, Andrea, Beck, Anita E, Morrison, Jennifer, Westman, Rachel, Averill, Kelly, Brunet, Theresa, Haasters, Judith, Carter, Melissa T, Osmond, Matthew, Wheeler, Patricia G, Forzano, Francesca, Mohammed, Shehla, Trakadis, Yannis, Accogli, Andrea, Harrison, Rachel, Guo, Yiran, Hakonarson, Hakon, Rondeau, Sophie, Baujat, Geneviève, Barcia, Giulia, Feichtinger, René Günther, Mayr, Johannes Adalbert, Preisel, Martin, Laumonnier, Frédéric, Kallinich, Tilmann, Knaus, Alexej, Isidor, Bertrand, Krawitz, Peter, Völker, Uwe, Hammer, Elke, Droit, Arnaud, Eichler, Evan E, Elgersma, Ype, Hildebrand, Peter W, Bolduc, François, Krüger, Elke, Bézieau, Stéphane

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Improving emergency department flow by introducing four interventions simultaneously. A quality improvement project by Van der Linden, M.C. (Christien), Van Loon-van Gaalen, M. (Merel), Meylaerts, S.A.G. (Sven), Quarles Van Ufford, H.M.E. (Jet), Woldhek, A. (Annemarie), Van Woerden, G. (Geesje), Van der Linden, N. (Naomi)

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GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain by Leurs, Ulrike, Klein, Anders B., McSpadden, Ethan D., Griem-Krey, Nane, Solbak, Sara M. Ø., Houlton, Josh, Villumsen, Inge S., Vogensen, Stine B., Hamborg, Louise, Gauger, Stine J., Palmelund, Line B., Larsen, Anne Sofie G., Shehata, Mohamed A., Kelstrup, Christian D., Olsen, Jesper V., Bach, Anders, Burnie, Robert O., Kerr, D. Steven, Gowing, Emma K., Teurlings, Selina M. W., Chi, Chris C., Gee, Christine L., Frølund, Bente, Kornum, Birgitte R., van Woerden, Geeske M., Clausen, Rasmus P., Kuriyan, John, Clarkson, Andrew N., Wellendorph, Petrine

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