Cs2CO3-Promoted Efficient Carbonate and Carbamate Synthesis on Solid Phase

Mild and efficient preparation of alkyl carbonates and carbamates on solid supports is described herein. Alcohols or amines were coupled with Merrifield's resin through a CO2 linker in the presence of cesium carbonate and tetrabutylammonium iodide (TBAI).

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Bibliographic Details
Published in:Organic letters 2000-09, Vol.2 (18), p.2797-2800
Main Authors: Salvatore, Ralph N, Flanders, Vincent L, Ha, Dang, Jung, Kyung Woon
Format: Article
Language:English
Online Access:Get full text
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Description
Summary:Mild and efficient preparation of alkyl carbonates and carbamates on solid supports is described herein. Alcohols or amines were coupled with Merrifield's resin through a CO2 linker in the presence of cesium carbonate and tetrabutylammonium iodide (TBAI).
ISSN:1523-7060
1523-7052
DOI:10.1021/ol006212i