Metalation of Iminium Ions Formed in the Reaction of Tertiary Amines with TiCl4

TiCl4 reacts with trialkylamines at 0−25 °C to give iminium ions that on metalation followed by reaction with diaryl ketones, produce α,β-unsaturated aldehydes.

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Bibliographic Details
Published in:Organic letters 1999-09, Vol.1 (6), p.857-859
Main Authors: Bharathi, Pandi, Periasamy, Mariappan
Format: Article
Language:English
Online Access:Get full text
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Description
Summary:TiCl4 reacts with trialkylamines at 0−25 °C to give iminium ions that on metalation followed by reaction with diaryl ketones, produce α,β-unsaturated aldehydes.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol990745d