Efficacy of Novel Rifamycin Derivatives against Rifamycin-Sensitive and -Resistant Staphylococcus aureus Isolates in Murine Models of Infection

• Published in: Antimicrobial Agents and Chemotherapy 2006-11, Vol.50 (11), p.3658-3664
• Main Authors: ROTHSTEIN, David M, FARQUHAR, Ronald S, SIROKMAN, Klari, SONDERGAARD, Karen L, HAZLETT, Charles, DOYE, Angelia A, GWATHMEY, Judith K, MULLIN, Steve, VAN DUZER, John, MURPHY, Christopher K
• Format: Article
• Language: English
• Subjects: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - pharmacology; Anti-Bacterial Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Chemistry, Pharmaceutical; Drug Resistance, Bacterial; Experimental Therapeutics; Medical sciences; Mice; Microbial Sensitivity Tests; Muscle, Skeletal - microbiology; Mutation; Neutropenia - complications; Pharmacology. Drug treatments; Rifamycins; Rifamycins - administration & dosage; Rifamycins - pharmacology; Rifamycins - therapeutic use; Sepsis - drug therapy; Sepsis - microbiology; Staphylococcal Infections; Staphylococcal Infections - microbiology; Staphylococcus aureus; Staphylococcus aureus - drug effects; Staphylococcus aureus - genetics; Structure-Activity Relationship
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.01087-05

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