Pharmacodynamics of vancomycin alone and in combination with gentamicin at various dosing intervals against methicillin-resistant Staphylococcus aureus-infected fibrin-platelet clots in an in vitro infection model

• Published in: Antimicrobial Agents and Chemotherapy 1997-11, Vol.41 (11), p.2497-2501
• Main Authors: HOULIHAN, H. H, MERCIER, R.-C, RYBAK, M. J
• Format: Article
• Language: English
• Subjects: Anti-Bacterial Agents; Anti-Bacterial Agents - pharmacokinetics; Anti-Bacterial Agents - pharmacology; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Area Under Curve; Biological and medical sciences; Blood Platelets - cytology; Cells, Cultured; Colony Count, Microbial; Comparative Study; Drug Therapy, Combination; Drug Therapy, Combination - pharmacokinetics; Drug Therapy, Combination - pharmacology; Fibrin; Gentamicins; Gentamicins - pharmacokinetics; Gentamicins - pharmacology; Humans; Medical sciences; Methicillin Resistance; Microbial Sensitivity Tests; Models, Biological; Pharmacology. Drug treatments; Staphylococcus aureus; Staphylococcus aureus - drug effects; Staphylococcus aureus - growth & development; Vancomycin; Vancomycin - pharmacokinetics; Vancomycin - pharmacology
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.41.11.2497

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