Anti-Hepatitis B Virus Activity and Metabolism of 2′,3′-Dideoxy-2′,3′-Didehydro-β-l(−)-5-Fluorocytidine

• Published in: Antimicrobial Agents and Chemotherapy 1998-07, Vol.42 (7), p.1805-1810
• Main Authors: ZHU, Y.-L, DUTSCHMAN, G. E, LIU, S.-H, BRIDGES, E. G, CHENG, Y.-C
• Format: Article
• Language: English
• Subjects: AIDS/HIV; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - metabolism; Antiviral Agents - pharmacology; Biological and medical sciences; Biological Products - metabolism; Deoxycytidine - analogs & derivatives; Deoxycytidine - metabolism; Deoxycytidine - pharmacology; Deoxycytidine Kinase - metabolism; DNA-Directed DNA Polymerase - metabolism; Dose-Response Relationship, Drug; Hepatitis B virus; Hepatitis B virus - drug effects; Humans; Lamivudine - metabolism; Lamivudine - pharmacology; Medical sciences; Pharmacology. Drug treatments; Phosphorylation; Reverse Transcriptase Inhibitors - metabolism; Reverse Transcriptase Inhibitors - pharmacology; Tumor Cells, Cultured; Zalcitabine; Zalcitabine - analogs & derivatives; Zalcitabine - metabolism; Zalcitabine - pharmacology
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.42.7.1805

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