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Anti-Oxidant Protective Effects of Cassia alata in Rats Exposed to Carbon Tetrachloride
The protective activity of Cassia alata against carbon tetrachloride (CCl4) - induced hepatotoxicity in rats was assessed. Crude extracts of petals of the plant in 0.5% ethanol were administered by intubation for 14 days prior to injection of 0.5ml Kg-1 CCl4 into the rats. Serum aspartate aminotrans...
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| Published in: | Journal of applied science & environmental management 2005-12, Vol.9 (3) |
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| Format: | Article |
| Language: | English |
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| container_title | Journal of applied science & environmental management |
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| creator | WEGWU, M O AYALOGU, E O SULE, O J |
| description | The protective activity of Cassia alata against carbon tetrachloride
(CCl4) - induced hepatotoxicity in rats was assessed. Crude extracts of
petals of the plant in 0.5% ethanol were administered by intubation for
14 days prior to injection of 0.5ml Kg-1 CCl4 into the rats. Serum
aspartate aminotransferase and alanine aminotransferase levels, 18
hours after CCl4 administration, decreased significantly (P ≤
0.05) in rats treated with the extracts than in CCl4 - treated rats
only. These findings suggest that Cassia alata may be protective
against hepatotoxin-induced liver damage in rats.@JASEM |
| format | article |
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(CCl4) - induced hepatotoxicity in rats was assessed. Crude extracts of
petals of the plant in 0.5% ethanol were administered by intubation for
14 days prior to injection of 0.5ml Kg-1 CCl4 into the rats. Serum
aspartate aminotransferase and alanine aminotransferase levels, 18
hours after CCl4 administration, decreased significantly (P ≤
0.05) in rats treated with the extracts than in CCl4 - treated rats
only. These findings suggest that Cassia alata may be protective
against hepatotoxin-induced liver damage in rats.@JASEM</description><identifier>ISSN: 1119-8362</identifier><language>eng</language><publisher>World Bank assisted National Agricultural Research Project (NARP) - University of Port Harcourt</publisher><ispartof>Journal of applied science & environmental management, 2005-12, Vol.9 (3)</ispartof><rights>Copyright 2005 - Journal of Applied Sciences & Environmental Management</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids></links><search><creatorcontrib>WEGWU, M O; AYALOGU, E O; SULE, O J</creatorcontrib><title>Anti-Oxidant Protective Effects of Cassia alata in Rats Exposed to Carbon Tetrachloride</title><title>Journal of applied science & environmental management</title><description>The protective activity of Cassia alata against carbon tetrachloride
(CCl4) - induced hepatotoxicity in rats was assessed. Crude extracts of
petals of the plant in 0.5% ethanol were administered by intubation for
14 days prior to injection of 0.5ml Kg-1 CCl4 into the rats. Serum
aspartate aminotransferase and alanine aminotransferase levels, 18
hours after CCl4 administration, decreased significantly (P ≤
0.05) in rats treated with the extracts than in CCl4 - treated rats
only. These findings suggest that Cassia alata may be protective
against hepatotoxin-induced liver damage in rats.@JASEM</description><issn>1119-8362</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNqVi0sKwjAURTNQsH728DZQST_WOpRScaZIwWF5bRN8JSYlCVJ3bwe6AOHCuZzLnbEgiqJDmCdZvGBL53rO432apwG7H7Wn8DJSh9rD1RovWk8vAaWUU3NgJBToHCGgQo9AGm44-XIcjBMdeDPttjEaKuEttg9lLHVizeYSlRObL1dseyqr4hw2ZBRpUQ-WnmjfdWsJ65_scQrf8SxO_j58APk7Sro</recordid><startdate>20051228</startdate><enddate>20051228</enddate><creator>WEGWU, M O; AYALOGU, E O; SULE, O J</creator><general>World Bank assisted National Agricultural Research Project (NARP) - University of Port Harcourt</general><scope>RBI</scope></search><sort><creationdate>20051228</creationdate><title>Anti-Oxidant Protective Effects of Cassia alata in Rats Exposed to Carbon Tetrachloride</title><author>WEGWU, M O; AYALOGU, E O; SULE, O J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-bioline_primary_cria_bioline_ja_ja050623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><toplevel>online_resources</toplevel><creatorcontrib>WEGWU, M O; AYALOGU, E O; SULE, O J</creatorcontrib><collection>Bioline International</collection><jtitle>Journal of applied science & environmental management</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>WEGWU, M O; AYALOGU, E O; SULE, O J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti-Oxidant Protective Effects of Cassia alata in Rats Exposed to Carbon Tetrachloride</atitle><jtitle>Journal of applied science & environmental management</jtitle><date>2005-12-28</date><risdate>2005</risdate><volume>9</volume><issue>3</issue><issn>1119-8362</issn><abstract>The protective activity of Cassia alata against carbon tetrachloride
(CCl4) - induced hepatotoxicity in rats was assessed. Crude extracts of
petals of the plant in 0.5% ethanol were administered by intubation for
14 days prior to injection of 0.5ml Kg-1 CCl4 into the rats. Serum
aspartate aminotransferase and alanine aminotransferase levels, 18
hours after CCl4 administration, decreased significantly (P ≤
0.05) in rats treated with the extracts than in CCl4 - treated rats
only. These findings suggest that Cassia alata may be protective
against hepatotoxin-induced liver damage in rats.@JASEM</abstract><pub>World Bank assisted National Agricultural Research Project (NARP) - University of Port Harcourt</pub></addata></record> |
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| identifier | ISSN: 1119-8362 |
| ispartof | Journal of applied science & environmental management, 2005-12, Vol.9 (3) |
| issn | 1119-8362 |
| language | eng |
| recordid | cdi_bioline_primary_cria_bioline_ja_ja05062 |
| source | Free Full-Text Journals in Chemistry |
| title | Anti-Oxidant Protective Effects of Cassia alata in Rats Exposed to Carbon Tetrachloride |
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