SPASMOLYTIC, ANTI-INFLAMMATORY, AND ANTIOXIDANT ACTIVITIES OF SALVIA GESNERIFLORA LINDLEY

Background: Salvia gesneriflora Lindley is employed in traditional Mexican medicine for the treatment of several diseases. This work reports the spasmolytic, anti-inflammatory and antioxidant activities of salvia gesneriflora Materials and Methods: The chromatographic profile of three extracts (SgH,...

Full description

Saved in:
Bibliographic Details
Published in:African journal of traditional, complementary, and alternative medicines complementary, and alternative medicines, 2019-05, Vol.15 (4)
Main Authors: Gómez-Rivera, Abraham, González-Cortazar, Manasés, Gallegos-García, Ammy Joana, Escobar-Ramos, Armando, Flores-Franco, Gabriel, Lobato-García, Carlos Ernesto
Format: Article
Language:English
Subjects:
anti-inflammatory
antioxidant activity
Salvia gesneriflora Lindley
spasmodic
spasmolytic
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: Salvia gesneriflora Lindley is employed in traditional Mexican medicine for the treatment of several diseases. This work reports the spasmolytic, anti-inflammatory and antioxidant activities of salvia gesneriflora Materials and Methods: The chromatographic profile of three extracts (SgH, SgD and SgM) of this plant allowed the identification of 11 components in SgH, the presence of rosmarinic (1), chlorogenic (2) and caffeic (3) acids and quercetin glucoside (4) in SgM and of ursolic acid (5) in SgD. The spasmolytic (electrically-induced contractions of guinea-pig ileum), anti-inflammatory (edema in mouse ear) and antioxidant potential (DPPH, ABTS and FRAP assays) of the extracts were evaluated. Results: SgM showed the highest percentage of relaxation (80.67 ± 1.633%) with no significant difference (p
ISSN:0189-6016