Tuberous sclerosis with visceral leishmaniasis: a case report

Introduction Visceral leishmaniasis, a tropical infectious disease, is a major public health problem in India. Tuberous sclerosis, a congenital neuro-ectodermosis, is an uncommon disease which requires life long treatment. Case presentation A 15-year-old Indian patient, presented to the outpatient d...

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Bibliographic Details
Published in:Journal of medical case reports 2009-09, Vol.3 (1), p.9027-9027
Main Authors: Lal, Chandra S, Verma, Rakesh B, Siddiqui, NA, Sinha, Prabhat K, Bimal, Sanjiva, Topno, Roshan K, Kumar, Nawin, Pandey, Krishna, Verma, Neena, Singh, Dharmendra, Das, Pradeep, Das, Vidyanand R
Format: Article
Language:English
Subjects:
Anticonvulsants
Care and treatment
Case studies
Diagnosis
Dosage and administration
Drug therapy
Kala-azar
Tuberous sclerosis
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Summary:Introduction Visceral leishmaniasis, a tropical infectious disease, is a major public health problem in India. Tuberous sclerosis, a congenital neuro-ectodermosis, is an uncommon disease which requires life long treatment. Case presentation A 15-year-old Indian patient, presented to the outpatient department of our institute with a high-grade fever for two months, splenomegaly and a history of generalized tonic-clonic convulsions since childhood. The clinical and laboratory findings suggested visceral leishmaniasis with tuberous sclerosis. The patient was treated with miltefosine and antiepileptics. Conclusion The patient responded well and in a follow up six months after presentation, she was found free of visceral leishmaniasis and seizures. Diagnosis and treatment of this rare combination of diseases is difficult.
ISSN:1752-1947
1752-1947
DOI:10.1186/1752-1947-0003-0000009027