Improved one-pot synthesis of N, N-diisopropyl-3-(2-Hydroxy-5-methylphenyl)-3-phenyl propanamide; a key intermediate for the preparation of racemic Tolterodine

An improved, cost effective process for the synthesis of N,N -diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropanamide; a key intermediate for the preparation of Tolterodine and its related substances were described. The process features one pot synthesis employing inexpensive reagents.

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Bibliographic Details
Published in:Sustainable chemical processes 2014-01, Vol.2 (1), p.1-2, Article 2
Main Authors: Srinivas, Garaga, Reddy, Ambati V Raghava, Prabahar, Koilpillai Joseph, Prasada Rao, Korrapati venkata vara, Sanasi, Paul Douglas, Korupolu, Raghubabu
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Reagents
Research Article
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Summary:An improved, cost effective process for the synthesis of N,N -diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropanamide; a key intermediate for the preparation of Tolterodine and its related substances were described. The process features one pot synthesis employing inexpensive reagents.
ISSN:2043-7129
2043-7129
DOI:10.1186/2043-7129-2-2