Effects of two medicinal plants Psidium guajava L. （Myrtaceae） and Diospyros mespiliformis L. （Ebenaceae） leaf extracts on rat skeletal muscle cells in primary culture

Crude decoction, aqueous and ethanolic extracts of two medicinal plants （Psidiura guajava and Diospyros raespiliformis）, widely used in the central plateau of Burkina Faso to treat many diseases were evaluated for their antagonistic effects on caffeine induced calcium release from sarcoplasmic retic...

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Bibliographic Details
Published in:Journal of Zhejiang University. B. Science 2006, Vol.7 (1), p.56-63
Main Author: BELEMTOUGRI R.G CONSTANTIN B. COGNARD C. RAYMOND G. SAWADOGO L
Format: Article
Language:English
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Summary:Crude decoction, aqueous and ethanolic extracts of two medicinal plants （Psidiura guajava and Diospyros raespiliformis）, widely used in the central plateau of Burkina Faso to treat many diseases were evaluated for their antagonistic effects on caffeine induced calcium release from sarcoplasmic reticulum of rat skeletal muscle cells. These different extracts showed a decrease of caffeine induced calcium release in a dose dependent manner. Comparison of the results showed that Psidiura guajava leaf extracts are more active than extracts of Diospyros mespiliformis and that crude decoctions show better inhibitory activity. The observed results could explaine their use as antihypertensive and antidiarrhoeal agents in traditional medicine, by inhibiting intracellular calcium release.
ISSN:1673-1581
1862-1783