Effect of Different Laser on Rats with Hypolekocytosis

• Published in: Journal of acupuncture and tuina science 2008, Vol.6 (5), p.300-300
• Main Author: 邓海平 沈雪勇 赵玲 黄奏琴 王敏 尚妍妍
• Format: Article
• Language: English
• Subjects: 中医治疗; 动物实验
• ISSN: 1672-3597; 1993-0399

Objective： To assess the effect of 10.6 pm laser and 650 nm laser simultaneous or separate irradiation on rats with hypolekocytosis. Methods： 60 Wistar Rats, 50% male and 50% female with normal white cell count （WBC） in blood and weight 180-220g, were randomly allocated to control, model, sham laser, 10.6μm laser, 650 nm laser and 10.6 μm＋650 nm laser group, 10 in each group. The hypolekocytosis model was established by i.p. cyclophosphamide 100g/kg weight. Corresponding laser irradiation was administration on Zusanli （ST 36） and Dazhui （GV 14） for 1 min, once per day, 8 times totally. The WBC in blood collected from tail end every two days after the model was established was taken as assess index. Results： The WBC of rats decreased continuely from the second day after injected cyclophosphamide, and to the lowest level on the fifth day, then began to recover. The WBC of 10.6 μm ＋650 nm laser group reached the normal level after 8 times laser irradiation, and had no difference with the control group （P〉0.01）, but the model, sham laser, 10.6 μm laser and 650 nm laser group had very significant difference with the control group （P〈0.001）.