Color Doppler sonography and angioscintigraphy in hepatic Hodgkin＇s lymphoma

• Published in: World journal of gastroenterology : WJG 2009 (26), p.3269-3275
• Main Author: Mirjana V Stojkovic Vera M Artiko Irena B Radoman Slavko J Knezevic Snezana M Lukic Mirko D Kerkez Nebojsa S Lekic Andrija A Antic Marinko M Zuvela Vitomir I Rankovic Milorad N Petrovic Dragana P Sobic Vladimir B Obradovic
• Format: Article
• Language: English
• Subjects: 多普勒超声; 强度估计; 彩色多普勒; 放射性核素; 淋巴瘤; 肝脏病变; 血流灌注
• ISSN: 1007-9327; 2219-2840

AIM： To estimate the characteristics of Color Doppler findings and the results of hepatic radionuclide angiography （HRA） in secondary Hodgkin＇s hepatic lymphoma. METHODS： The research included patients with a diagnosis of Hodgkin＇s lymphoma with metastatic focal lesions in the liver and controls. Morphologic characteristics of focal liver lesions and hemodynamic parameters were examined by pulsed and Color Doppler in the portal, hepatic and splenic veins were examined. Hepatic perfusion index （HPI） estimated by HRA was calculated. was observed. Lesions were mostly hypoechoic and mixed, solitary or multiple. Some of the patients presented with dilated splenic veins and hepatofugal blood flow. A pulse wave was registered in the centre and at the margins of lymphoma. The average velocity of the pulse wave was higher at the margins （P 〉 0.05）. A continuous venous wave was found only at the margins of lymphoma. There was no linear correlation between lymphoma size and velocity of pulse and continuous wave （r = 390, P 〈 0.01）. HPI was significantly lower in patients with lymphomas than in controls （P 〈 0.05）, pointing out increased arterial perfusion in comparison to portal perfusion. CONCLUSION： Color Doppler ultrasonography is a sensitive method for the detection of neovascularization in Hodgkin＇s hepatic lymphoma and estimation of its intensity. Hepatic radionuclide angiography can additionally help in the assesment of vascularisation of liver lesions.