Microwave-assisted synthesis of α-hydroxy aromatic ketones from ot-bromo aromatic ketones in water

A reaction of α-bromo aromatic ketones in water with microwave irradiation gave the corresponding α-hydroxy aromatic ketones in good yields. The use of microwaves was found to significantly improve yields and shorten the reaction time. This reaction afforded a very clean, convenient method for the s...

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Bibliographic Details
Published in:Chinese chemical letters 2011, Vol.22 (1), p.53-56
Main Author: Xiang Liu Hai Bo Chen Zheng Guang Pan Jian He Xu He Xing Li
Format: Article
Language:English
Subjects:
催产素
反应合成
微波辅助合成
芳香酮
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Summary:A reaction of α-bromo aromatic ketones in water with microwave irradiation gave the corresponding α-hydroxy aromatic ketones in good yields. The use of microwaves was found to significantly improve yields and shorten the reaction time. This reaction afforded a very clean, convenient method for the synthesis of α-hydroxy aromatic ketones.
ISSN:1001-8417
1878-5964