BINDING OF THERMO-SENSITIVE AND pH-SENSITIVE BUTYLATED POLY（ALLYLAMINE）S WITH LYSOZYME

Butyl modified poly（allylamine）s with butyl substitution degrees of 15% to 70% were prepared. The polymers show pH sensitive property and lower critical solution temperature （LCST） behavior. The LCST appears at lower temperature, lower pH and lower polymer concentration for the polymer with higher b...

Full description

Saved in:
Bibliographic Details
Published in:高分子科学：英文版 2011, Vol.29 (4), p.397-406
Main Author: Jing-jing Liu Yun-feng Yan Ping Yao
Format: Article
Language:English
Subjects:
pH敏感
丁基化
丙烯胺
低临界溶解温度
溶菌酶
热敏感
约束力
聚合物浓度
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 406
container_issue 4
container_start_page 397
container_title 高分子科学：英文版
container_volume 29
creator Jing-jing Liu Yun-feng Yan Ping Yao
description Butyl modified poly（allylamine）s with butyl substitution degrees of 15% to 70% were prepared. The polymers show pH sensitive property and lower critical solution temperature （LCST） behavior. The LCST appears at lower temperature, lower pH and lower polymer concentration for the polymer with higher butylated degree. The binding of native lysozyme with the polymers depends on the hydrophobicity of the polymers at the pH range that the protein and the polymer carry the same positive charges. The increase of polymer hydrophobicity can increase the binding with lysozyme, but the self-aggregation of the polymer decreases the binding. The bound lysozyme molecules can recover their native activity completely after the dissociation of the complexes. Compared with native lysozyme, the denatured one which exposes the hydrophobic residues can increase the binding with the polymer and form stable complex nanoparticles.
format article
fullrecord <record><control><sourceid>chongqing</sourceid><recordid>TN_cdi_chongqing_primary_38141838</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>38141838</cqvip_id><sourcerecordid>38141838</sourcerecordid><originalsourceid>FETCH-chongqing_primary_381418383</originalsourceid><addsrcrecordid>eNpjYuA0NDG21DUzMjBmYeA0MDI10zU3M7fkYOAqLs4yMDAzMTc152SIcvL0c_H0c1fwd1MI8XAN8vXXDXb1C_YM8QxzVXD0c1Eo8EAScAoNifRxDHF1UQjw94l8v6fD0ccHKODr6ef6fk9nsEK4Z4iHgk9ksH9UpK8rDwNrWmJOcSovlOZmUHRzDXH20E3OyM9LL8zMS48vKMrMTSyqjDe2MDQxtDC2MCZGDQAbOz1s</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>BINDING OF THERMO-SENSITIVE AND pH-SENSITIVE BUTYLATED POLY（ALLYLAMINE）S WITH LYSOZYME</title><source>Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List</source><creator>Jing-jing Liu Yun-feng Yan Ping Yao</creator><creatorcontrib>Jing-jing Liu Yun-feng Yan Ping Yao</creatorcontrib><description>Butyl modified poly（allylamine）s with butyl substitution degrees of 15% to 70% were prepared. The polymers show pH sensitive property and lower critical solution temperature （LCST） behavior. The LCST appears at lower temperature, lower pH and lower polymer concentration for the polymer with higher butylated degree. The binding of native lysozyme with the polymers depends on the hydrophobicity of the polymers at the pH range that the protein and the polymer carry the same positive charges. The increase of polymer hydrophobicity can increase the binding with lysozyme, but the self-aggregation of the polymer decreases the binding. The bound lysozyme molecules can recover their native activity completely after the dissociation of the complexes. Compared with native lysozyme, the denatured one which exposes the hydrophobic residues can increase the binding with the polymer and form stable complex nanoparticles.</description><identifier>ISSN: 0256-7679</identifier><identifier>EISSN: 1439-6203</identifier><language>eng</language><subject>pH敏感 ; 丁基化 ; 丙烯胺 ; 低临界溶解温度 ; 溶菌酶 ; 热敏感 ; 约束力 ; 聚合物浓度</subject><ispartof>高分子科学：英文版, 2011, Vol.29 (4), p.397-406</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/86788X/86788X.jpg</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids></links><search><creatorcontrib>Jing-jing Liu Yun-feng Yan Ping Yao</creatorcontrib><title>BINDING OF THERMO-SENSITIVE AND pH-SENSITIVE BUTYLATED POLY（ALLYLAMINE）S WITH LYSOZYME</title><title>高分子科学：英文版</title><addtitle>Chinese Journal of Polymer Science</addtitle><description>Butyl modified poly（allylamine）s with butyl substitution degrees of 15% to 70% were prepared. The polymers show pH sensitive property and lower critical solution temperature （LCST） behavior. The LCST appears at lower temperature, lower pH and lower polymer concentration for the polymer with higher butylated degree. The binding of native lysozyme with the polymers depends on the hydrophobicity of the polymers at the pH range that the protein and the polymer carry the same positive charges. The increase of polymer hydrophobicity can increase the binding with lysozyme, but the self-aggregation of the polymer decreases the binding. The bound lysozyme molecules can recover their native activity completely after the dissociation of the complexes. Compared with native lysozyme, the denatured one which exposes the hydrophobic residues can increase the binding with the polymer and form stable complex nanoparticles.</description><subject>pH敏感</subject><subject>丁基化</subject><subject>丙烯胺</subject><subject>低临界溶解温度</subject><subject>溶菌酶</subject><subject>热敏感</subject><subject>约束力</subject><subject>聚合物浓度</subject><issn>0256-7679</issn><issn>1439-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNpjYuA0NDG21DUzMjBmYeA0MDI10zU3M7fkYOAqLs4yMDAzMTc152SIcvL0c_H0c1fwd1MI8XAN8vXXDXb1C_YM8QxzVXD0c1Eo8EAScAoNifRxDHF1UQjw94l8v6fD0ccHKODr6ef6fk9nsEK4Z4iHgk9ksH9UpK8rDwNrWmJOcSovlOZmUHRzDXH20E3OyM9LL8zMS48vKMrMTSyqjDe2MDQxtDC2MCZGDQAbOz1s</recordid><startdate>2011</startdate><enddate>2011</enddate><creator>Jing-jing Liu Yun-feng Yan Ping Yao</creator><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>~WA</scope></search><sort><creationdate>2011</creationdate><title>BINDING OF THERMO-SENSITIVE AND pH-SENSITIVE BUTYLATED POLY（ALLYLAMINE）S WITH LYSOZYME</title><author>Jing-jing Liu Yun-feng Yan Ping Yao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-chongqing_primary_381418383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>pH敏感</topic><topic>丁基化</topic><topic>丙烯胺</topic><topic>低临界溶解温度</topic><topic>溶菌酶</topic><topic>热敏感</topic><topic>约束力</topic><topic>聚合物浓度</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jing-jing Liu Yun-feng Yan Ping Yao</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库- 镜像站点</collection><jtitle>高分子科学：英文版</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jing-jing Liu Yun-feng Yan Ping Yao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>BINDING OF THERMO-SENSITIVE AND pH-SENSITIVE BUTYLATED POLY（ALLYLAMINE）S WITH LYSOZYME</atitle><jtitle>高分子科学：英文版</jtitle><addtitle>Chinese Journal of Polymer Science</addtitle><date>2011</date><risdate>2011</risdate><volume>29</volume><issue>4</issue><spage>397</spage><epage>406</epage><pages>397-406</pages><issn>0256-7679</issn><eissn>1439-6203</eissn><abstract>Butyl modified poly（allylamine）s with butyl substitution degrees of 15% to 70% were prepared. The polymers show pH sensitive property and lower critical solution temperature （LCST） behavior. The LCST appears at lower temperature, lower pH and lower polymer concentration for the polymer with higher butylated degree. The binding of native lysozyme with the polymers depends on the hydrophobicity of the polymers at the pH range that the protein and the polymer carry the same positive charges. The increase of polymer hydrophobicity can increase the binding with lysozyme, but the self-aggregation of the polymer decreases the binding. The bound lysozyme molecules can recover their native activity completely after the dissociation of the complexes. Compared with native lysozyme, the denatured one which exposes the hydrophobic residues can increase the binding with the polymer and form stable complex nanoparticles.</abstract></addata></record>
fulltext fulltext
identifier ISSN: 0256-7679
ispartof 高分子科学：英文版, 2011, Vol.29 (4), p.397-406
issn 0256-7679
1439-6203
language eng
recordid cdi_chongqing_primary_38141838
source Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List
subjects pH敏感
丁基化
丙烯胺
低临界溶解温度
溶菌酶
热敏感
约束力
聚合物浓度
title BINDING OF THERMO-SENSITIVE AND pH-SENSITIVE BUTYLATED POLY（ALLYLAMINE）S WITH LYSOZYME
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T02%3A47%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-chongqing&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=BINDING%20OF%20THERMO-SENSITIVE%20AND%20pH-SENSITIVE%20BUTYLATED%20POLY%EF%BC%88ALLYLAMINE%EF%BC%89S%20WITH%20LYSOZYME&rft.jtitle=%E9%AB%98%E5%88%86%E5%AD%90%E7%A7%91%E5%AD%A6%EF%BC%9A%E8%8B%B1%E6%96%87%E7%89%88&rft.au=Jing-jing%20Liu%20Yun-feng%20Yan%20Ping%20Yao&rft.date=2011&rft.volume=29&rft.issue=4&rft.spage=397&rft.epage=406&rft.pages=397-406&rft.issn=0256-7679&rft.eissn=1439-6203&rft_id=info:doi/&rft_dat=%3Cchongqing%3E38141838%3C/chongqing%3E%3Cgrp_id%3Ecdi_FETCH-chongqing_primary_381418383%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rft_cqvip_id=38141838&rfr_iscdi=true