Functional MRI study of mild Alzheimer＇s disease using amplitude of low frequency fluctuation analysis

Background Previous studies have shown that the functional brain activity in the resting state is impaired in Alzheimer＇s disease （AD） patients. However, most studies focused on the relationship between different brain areas, rather than the amplitude or strength of the regional brain activity. The...

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Bibliographic Details
Published in:中华医学杂志：英文版 2012 (5), p.858-862
Main Author: XI Qian ZHAO Xiao-hu WANG Pei-jun GUO Qi-hao YAN Chao-gan HE Yong
Format: Article
Language:English
Subjects:
低频
功能变化
功能磁共振成像
大脑活动
振幅
波动分析
阿尔茨海默氏病
静止状态
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Summary:Background Previous studies have shown that the functional brain activity in the resting state is impaired in Alzheimer＇s disease （AD） patients. However, most studies focused on the relationship between different brain areas, rather than the amplitude or strength of the regional brain activity. The purpose of this study was to explore the functional brain changes in AD patients by measuring the amplitude of the blood oxygenation level dependent （BOLD） functional MRI （fMRI） signals.
ISSN:0366-6999
2542-5641