Evolution of the 4-coumarate：coenzyme A ligase （4CL） gene family： Conserved evolutionary pattern and two new gene classes in gymnosperms

The 4-coumarate：coenzyme A ligase （4CL） is the branch point enzyme that channels the general phenyl- propanoid metabolism into specific lignin and flavonoid biosynthesis branches. Genetic engineering experiments on the 4CL gene have been carried out in many species, but the precise functions of diff...

Full description

Saved in:
Bibliographic Details
Published in:植物分类学报：英文版 2012, Vol.50 (3), p.195-205
Main Author: Hui GAO Dong-Mei GUO Wen-Juan LIU Jin-Hua RAN Xiao-Quan WANG
Format: Article
Language:English
Subjects:
4CL
基因家族
新基因
植物类
辅酶A
进化模式
连接酶
香豆酸
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The 4-coumarate：coenzyme A ligase （4CL） is the branch point enzyme that channels the general phenyl- propanoid metabolism into specific lignin and flavonoid biosynthesis branches. Genetic engineering experiments on the 4CL gene have been carried out in many species, but the precise functions of different gene members are still unresolved. To investigate the evolutionary relationships and functional differentiation of the 4CL gene family, we made a comprehensive evolutionary analysis of this gene family from 27 species representing the major lineages of land plants. The phylogenetic analysis indicates that both vascular and seed plant 4CL genes form monophyletic groups, and that three and two 4CL classes can be recognized in gymnosperms and angiosperms, respectively. The evolutionary rate and frequency of duplication of the 4CL gene family are much more conserved than that of the CAD~SAD （cinnamyl/sinapyl alcohol dehydrogenase） gene family, which catalyzes the last step in monolignol biosynthesis. This may be due to different selective pressures on these genes whose products catalyze different steps in the biosynthesis pathway. In addition, we found two new major classes of 4CL genes in gymnosperms.
ISSN:1674-4918
1759-6831