Feasibility of similarity coefficient map for improving morphological evaluation of T2＊ weighted MRI for renal cancer

• Published in: 中国物理B：英文版 2013-03 (3), p.539-549
• Main Author: 王浩宇 Hu Jiani 谢耀钦 陈杰 Yu Amy 魏新华 戴勇鸣 Li Meng 包尚联 E.M.Haacke
• Format: Article
• Language: English
• Subjects: MRI; 供应链管理系统; 加权; 单片机技术; 形态学; 相似系数; 评价; 黑白图像
• ISSN: 1674-1056; 2058-3834
• DOI: 10.1088/1674-1056/22/3/038702

The purpose of this paper is to investigate the feasibility of using a similarity coefficient map（SCM） in improving the morphological evaluation of T2＊ weighted（T2＊W） magnatic resonance imaging（MRI） for renal cancer.Simulation studies and in vivo 12-echo T2＊W experiments for renal cancers were performed for this purpose.The results of the first simulation study suggest that an SCM can reveal small structures which are hard to distinguish from the background tissue in T2＊W images and the corresponding T2＊ map.The capability of improving the morphological evaluation is likely due to the improvement in the signal-to-noise ratio（SNR） and the carrier-to-noise ratio（CNR） by using the SCM technique.Compared with T2＊ W images,an SCM can improve the SNR by a factor ranging from 1.87 to 2.47.Compared with T2＊ maps,an SCM can improve the SNR by a factor ranging from 3.85 to 33.31.Compared with T2＊W images,an SCM can improve the CNR by a factor ranging from 2.09 to 2.43.Compared with T2＊ maps,an SCM can improve the CNR by a factor ranging from 1.94 to 8.14.For a given noise level,the improvements of the SNR and the CNR depend mainly on the original SNRs and CNRs in T2＊W images,respectively.In vivo experiments confirmed the results of the first simulation study.The results of the second simulation study suggest that more echoes are used to generate the SCM,and higher SNRs and CNRs can be achieved in SCMs.In conclusion,an SCM can provide improved morphological evaluation of T2＊W MR images for renal cancer by unveiling fine structures which are ambiguous or invisible in the corresponding T2＊W MR images and T2＊ maps.Furthermore,in practical applications,for a fixed total sampling time,one should increase the number of echoes as much as possible to achieve SCMs with better SNRs and CNRs.