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Late Neolithic expansion of ancient Chinese revealed by Y chromosome haplogroup O3alc-002611

Y chromosome haplogroup O3-M122 is the most prevalent haplogroup in East Asia, and provides an ideal tool for dissecting primary dispersals of the East Asians. Most of the sub-haplogroups of O3-M122 have been sufficiently investigated except for O3al c-002611, despite its great prevalence and huge p...

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Published in:植物分类学报:英文版 2013, Vol.51 (3), p.280-286
Main Author: Chuan-Chao WANG Shi YAN Zhen-Dong QIN Yah LU Qi-Liang DING Lan-Hai WEI Shi-Lin LI Ya-Jun YANG Li JIN Hui LI Genographic Consortium
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Language:English
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Summary:Y chromosome haplogroup O3-M122 is the most prevalent haplogroup in East Asia, and provides an ideal tool for dissecting primary dispersals of the East Asians. Most of the sub-haplogroups of O3-M122 have been sufficiently investigated except for O3al c-002611, despite its great prevalence and huge population, especially in Han Chinese. In this study, we identified 508 individuals with haplogroup O3alc-002611 out of 7801 males from 117 East and Southeast Asian populations, typed at two newly discovered downstream Y-SNP markers and ten commonly used Y-STRs. Defined by SNPs IMS-JST002611 (in short, 002611), F11, and F238, three lineages internal to haplogroup O3alc-002611 have distinct geographical distributions. Furthermore, Y-STR diversity shows a general south-to- north decline, which is consistent with the prehistorically northward migration of the other O3-M122 lineages. The northward migration ofhaplogroup O3alc-002611 started about 13 thousand years ago (KYA). The expansions of subclades F11 and F238 in ancient Han Chinese began about 5 and 7 KYA immediately after the separation between the ancestors of the Han Chinese and Tibeto-Burman.
ISSN:1674-4918
1759-6831