Loading…
BASIC STUDY Effect of Preventive Acupuncture and Moxibustion on Hypothalamus and Ovarian Leptin and Blood Lipid Levels in Menopausal Rats
Objective: To observe the changes of hypothalamus, ovarian leptin levels and blood lipid in 12-month-old rats with natural menopause, and the effect of preventive acupuncture and moxibustion at Guanyuan (CV 4). To explore the impact of preventive acupuncture and moxibustion on the internal environme...
Saved in:
Published in: | 针灸推拿医学:英文版 2013 (4), p.199-203 |
---|---|
Main Author: | |
Format: | Article |
Language: | English |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | |
---|---|
cites | |
container_end_page | 203 |
container_issue | 4 |
container_start_page | 199 |
container_title | 针灸推拿医学:英文版 |
container_volume | |
creator | Zhu Shi-peng Luo Li Sun Zhi-fang Ding Na Zhang Qing-qing He Yu-wei Zhang Lu-fen Li Xiao-hong |
description | Objective: To observe the changes of hypothalamus, ovarian leptin levels and blood lipid in 12-month-old rats with natural menopause, and the effect of preventive acupuncture and moxibustion at Guanyuan (CV 4). To explore the impact of preventive acupuncture and moxibustion on the internal environment of early menopause disorder. Methods: Menopausal female rats were screened by vaginal smear. Rat model of menopause was obtained by natural aging method. Preventive acupuncture and moxibustion at Guanyuan (CV 4) was used as intervention methods. Hypothalamus and ovarian leptin levels were detected by radioimmunoassay. Plasma total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) levels were determined by biochemical methods. Results: Compared with the young control group, leptin levels in the hypothalamus and ovarian increased (P〈0.01), plasma TC increased (P〈0.05), LDL increased (P〈0.01), and HDL reduced in 12-month-old rats. Hypothalamus and ovary leptin levels in 22-month-old rats with preventive acupuncture and moxibustion were significantly decreased (P〈0.01); plasma TC and LDL levels decreased and HDL levels were increased in rats with preventive acupuncture (P〈0.05). Conclusion: Preventive acupuncture and moxibustion can improve leptin resistance state and restore the abnormal lipid levels in menopausal body, and therefore can slow down the disorder of inner environment in early menopause. |
format | article |
fullrecord | <record><control><sourceid>chongqing</sourceid><recordid>TN_cdi_chongqing_primary_47065747</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>47065747</cqvip_id><sourcerecordid>47065747</sourcerecordid><originalsourceid>FETCH-chongqing_primary_470657473</originalsourceid><addsrcrecordid>eNqNTF1qAjEYDKWC1nqHrwdY2O66G_Ko1mJBaan60Cf5XLP6lZik-VnqEXrrBukBCsPMMDPMDRs8ClFmeSnEbfI1L7KyErzP7rz_zPOK10UxYD_TyfplBuvN9ukD5m0rmwCmhTcnO6kDdRImTbRRNyE6CagPsDLftI8-kNGQsLhYE06o8Bz9tX_t0BFqWEobSF-jqTLmAEuylDgdKw-pWUltLEaPCt4x-HvWa1F5OfrTIXt4nm9mi6w5GX38In3cWUdndJfdmOd1xce8_M_mF0fZUu4</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>BASIC STUDY Effect of Preventive Acupuncture and Moxibustion on Hypothalamus and Ovarian Leptin and Blood Lipid Levels in Menopausal Rats</title><source>Springer Nature</source><creator>Zhu Shi-peng Luo Li Sun Zhi-fang Ding Na Zhang Qing-qing He Yu-wei Zhang Lu-fen Li Xiao-hong</creator><creatorcontrib>Zhu Shi-peng Luo Li Sun Zhi-fang Ding Na Zhang Qing-qing He Yu-wei Zhang Lu-fen Li Xiao-hong</creatorcontrib><description>Objective: To observe the changes of hypothalamus, ovarian leptin levels and blood lipid in 12-month-old rats with natural menopause, and the effect of preventive acupuncture and moxibustion at Guanyuan (CV 4). To explore the impact of preventive acupuncture and moxibustion on the internal environment of early menopause disorder. Methods: Menopausal female rats were screened by vaginal smear. Rat model of menopause was obtained by natural aging method. Preventive acupuncture and moxibustion at Guanyuan (CV 4) was used as intervention methods. Hypothalamus and ovarian leptin levels were detected by radioimmunoassay. Plasma total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) levels were determined by biochemical methods. Results: Compared with the young control group, leptin levels in the hypothalamus and ovarian increased (P〈0.01), plasma TC increased (P〈0.05), LDL increased (P〈0.01), and HDL reduced in 12-month-old rats. Hypothalamus and ovary leptin levels in 22-month-old rats with preventive acupuncture and moxibustion were significantly decreased (P〈0.01); plasma TC and LDL levels decreased and HDL levels were increased in rats with preventive acupuncture (P〈0.05). Conclusion: Preventive acupuncture and moxibustion can improve leptin resistance state and restore the abnormal lipid levels in menopausal body, and therefore can slow down the disorder of inner environment in early menopause.</description><identifier>ISSN: 1672-3597</identifier><identifier>EISSN: 1993-0399</identifier><language>eng</language><ispartof>针灸推拿医学:英文版, 2013 (4), p.199-203</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/87251X/87251X.jpg</thumbnail><link.rule.ids>314,780,784,4024</link.rule.ids></links><search><creatorcontrib>Zhu Shi-peng Luo Li Sun Zhi-fang Ding Na Zhang Qing-qing He Yu-wei Zhang Lu-fen Li Xiao-hong</creatorcontrib><title>BASIC STUDY Effect of Preventive Acupuncture and Moxibustion on Hypothalamus and Ovarian Leptin and Blood Lipid Levels in Menopausal Rats</title><title>针灸推拿医学:英文版</title><addtitle>Journal of Acupuncture and Tuina Science</addtitle><description>Objective: To observe the changes of hypothalamus, ovarian leptin levels and blood lipid in 12-month-old rats with natural menopause, and the effect of preventive acupuncture and moxibustion at Guanyuan (CV 4). To explore the impact of preventive acupuncture and moxibustion on the internal environment of early menopause disorder. Methods: Menopausal female rats were screened by vaginal smear. Rat model of menopause was obtained by natural aging method. Preventive acupuncture and moxibustion at Guanyuan (CV 4) was used as intervention methods. Hypothalamus and ovarian leptin levels were detected by radioimmunoassay. Plasma total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) levels were determined by biochemical methods. Results: Compared with the young control group, leptin levels in the hypothalamus and ovarian increased (P〈0.01), plasma TC increased (P〈0.05), LDL increased (P〈0.01), and HDL reduced in 12-month-old rats. Hypothalamus and ovary leptin levels in 22-month-old rats with preventive acupuncture and moxibustion were significantly decreased (P〈0.01); plasma TC and LDL levels decreased and HDL levels were increased in rats with preventive acupuncture (P〈0.05). Conclusion: Preventive acupuncture and moxibustion can improve leptin resistance state and restore the abnormal lipid levels in menopausal body, and therefore can slow down the disorder of inner environment in early menopause.</description><issn>1672-3597</issn><issn>1993-0399</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqNTF1qAjEYDKWC1nqHrwdY2O66G_Ko1mJBaan60Cf5XLP6lZik-VnqEXrrBukBCsPMMDPMDRs8ClFmeSnEbfI1L7KyErzP7rz_zPOK10UxYD_TyfplBuvN9ukD5m0rmwCmhTcnO6kDdRImTbRRNyE6CagPsDLftI8-kNGQsLhYE06o8Bz9tX_t0BFqWEobSF-jqTLmAEuylDgdKw-pWUltLEaPCt4x-HvWa1F5OfrTIXt4nm9mi6w5GX38In3cWUdndJfdmOd1xce8_M_mF0fZUu4</recordid><startdate>2013</startdate><enddate>2013</enddate><creator>Zhu Shi-peng Luo Li Sun Zhi-fang Ding Na Zhang Qing-qing He Yu-wei Zhang Lu-fen Li Xiao-hong</creator><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope></search><sort><creationdate>2013</creationdate><title>BASIC STUDY Effect of Preventive Acupuncture and Moxibustion on Hypothalamus and Ovarian Leptin and Blood Lipid Levels in Menopausal Rats</title><author>Zhu Shi-peng Luo Li Sun Zhi-fang Ding Na Zhang Qing-qing He Yu-wei Zhang Lu-fen Li Xiao-hong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-chongqing_primary_470657473</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhu Shi-peng Luo Li Sun Zhi-fang Ding Na Zhang Qing-qing He Yu-wei Zhang Lu-fen Li Xiao-hong</creatorcontrib><collection>维普_期刊</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>维普中文期刊数据库</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><jtitle>针灸推拿医学:英文版</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhu Shi-peng Luo Li Sun Zhi-fang Ding Na Zhang Qing-qing He Yu-wei Zhang Lu-fen Li Xiao-hong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>BASIC STUDY Effect of Preventive Acupuncture and Moxibustion on Hypothalamus and Ovarian Leptin and Blood Lipid Levels in Menopausal Rats</atitle><jtitle>针灸推拿医学:英文版</jtitle><addtitle>Journal of Acupuncture and Tuina Science</addtitle><date>2013</date><risdate>2013</risdate><issue>4</issue><spage>199</spage><epage>203</epage><pages>199-203</pages><issn>1672-3597</issn><eissn>1993-0399</eissn><abstract>Objective: To observe the changes of hypothalamus, ovarian leptin levels and blood lipid in 12-month-old rats with natural menopause, and the effect of preventive acupuncture and moxibustion at Guanyuan (CV 4). To explore the impact of preventive acupuncture and moxibustion on the internal environment of early menopause disorder. Methods: Menopausal female rats were screened by vaginal smear. Rat model of menopause was obtained by natural aging method. Preventive acupuncture and moxibustion at Guanyuan (CV 4) was used as intervention methods. Hypothalamus and ovarian leptin levels were detected by radioimmunoassay. Plasma total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) levels were determined by biochemical methods. Results: Compared with the young control group, leptin levels in the hypothalamus and ovarian increased (P〈0.01), plasma TC increased (P〈0.05), LDL increased (P〈0.01), and HDL reduced in 12-month-old rats. Hypothalamus and ovary leptin levels in 22-month-old rats with preventive acupuncture and moxibustion were significantly decreased (P〈0.01); plasma TC and LDL levels decreased and HDL levels were increased in rats with preventive acupuncture (P〈0.05). Conclusion: Preventive acupuncture and moxibustion can improve leptin resistance state and restore the abnormal lipid levels in menopausal body, and therefore can slow down the disorder of inner environment in early menopause.</abstract></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1672-3597 |
ispartof | 针灸推拿医学:英文版, 2013 (4), p.199-203 |
issn | 1672-3597 1993-0399 |
language | eng |
recordid | cdi_chongqing_primary_47065747 |
source | Springer Nature |
title | BASIC STUDY Effect of Preventive Acupuncture and Moxibustion on Hypothalamus and Ovarian Leptin and Blood Lipid Levels in Menopausal Rats |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T09%3A20%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-chongqing&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=BASIC%20STUDY%20Effect%20of%20Preventive%20Acupuncture%20and%20Moxibustion%20on%20Hypothalamus%20and%20Ovarian%20Leptin%20and%20Blood%20Lipid%20Levels%20in%20Menopausal%20Rats&rft.jtitle=%E9%92%88%E7%81%B8%E6%8E%A8%E6%8B%BF%E5%8C%BB%E5%AD%A6%EF%BC%9A%E8%8B%B1%E6%96%87%E7%89%88&rft.au=Zhu%20Shi-peng%20Luo%20Li%20Sun%20Zhi-fang%20Ding%20Na%20Zhang%20Qing-qing%20He%20Yu-wei%20Zhang%20Lu-fen%20Li%20Xiao-hong&rft.date=2013&rft.issue=4&rft.spage=199&rft.epage=203&rft.pages=199-203&rft.issn=1672-3597&rft.eissn=1993-0399&rft_id=info:doi/&rft_dat=%3Cchongqing%3E47065747%3C/chongqing%3E%3Cgrp_id%3Ecdi_FETCH-chongqing_primary_470657473%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rft_cqvip_id=47065747&rfr_iscdi=true |