Sleep Duration and Risk of Lung Cancer in the Physicians＆#39; Health Study

Background and Objectives：Lung cancer is the most common cancer and cancer related cause of death worldwide. However, the association between sleep duration and incident lung cancer has not been investigated in a prospective cohort study. Methods：We prospectively examined the association between sle...

Full description

Saved in:
Bibliographic Details
Published in:中国肺癌杂志 2014, Vol.17 (9), p.649-655
Main Author: Owais KHAWAJA Andrew B. PETRONE SohaibATEEM Kamran MANZOOR John MGAZIANO Luc DJOUSSE
Format: Article
Language:Chinese
Subjects:
摘要
编辑工作
编辑部
读者
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background and Objectives：Lung cancer is the most common cancer and cancer related cause of death worldwide. However, the association between sleep duration and incident lung cancer has not been investigated in a prospective cohort study. Methods：We prospectively examined the association between sleep duration and incident lung cancer in a cohort of 21,026 United States （US） male physicians. Self-reported sleep duration was ascertained during 2002 annual follow-up questionnaire. Incident lung cancer was ascertained through yearly follow-up questionnaires. Cox regression was used to estimate relative risk of incident lung cancer. Results：hTe average age at baseline was 68.3±8.8 yr. During a mean follow up of 7.5 （±2.2） yr, 150 cases of lung cancer occurred. Using 7 h of sleep as the reference group, multivariable adjusted hazard ratios （95%CI） for lung cancer were 1.18 （0.77-1.82）, 1.0 （ref）, and 0.97 （0.67-1.41） from lowest to the highest category of sleep duration （P for quadratic trend 0.697）, respectively.
ISSN:1009-3419
1999-6187