Traditional Chinese Medicine for the treatment of influenza： a sys- tematic review and Meta-analysis of randomized controlled trials

OBJECTIVE： To justify the clinical use of Traditional Chinese Medicine（TCM） in the treatment of influenza.METHODS： MEDLINE, EMBASE, Chinese Biomedical Literature Database, China National Knowledge Infrastructure Database, China Science and Technology Journal Database, Wanfang Database and the Cochra...

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Published in:中医杂志：英文版 2014 (5), p.527-531
Main Author: Chunya Wang HaoWang XinyingLiu Dongping Xu YipingTang Ping Luo
Format: Article
Language:English
Subjects:
Meta分析
中国传统医学
医学文献数据库
审查
治疗
流感
系统化
随机对照试验
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Summary:OBJECTIVE： To justify the clinical use of Traditional Chinese Medicine（TCM） in the treatment of influenza.METHODS： MEDLINE, EMBASE, Chinese Biomedical Literature Database, China National Knowledge Infrastructure Database, China Science and Technology Journal Database, Wanfang Database and the Cochrane Database of Systematic Reviews were searched from thedate of inception until January 1,2013, for the literature on treatment of influenza with TCM.RESULTS： A total of 7 randomized controlled trials were identified and reviewed. Of these trials, 2 compared a（modified） prescription of TCM with oseltamivir and 5 compared a patent traditional Chinese drug with oseltamivir. Based on the Meta-analysis,compared to oseltamivir, the（modified） prescription had similar effect in defervescence [WMD=5.66, 95% CI（﹣32.02, 43.35）, P=0.77] and viral shedding [WMD=﹣ 6.21, 95% CI（﹣84.19, 71.76）, P=0.88], and the patent traditional Chinese drug also had similar effect in viral shedding [WMD=﹣ 0.24,95% CI（﹣4.79, 4.31）, P=0.92] but more effective in defervescence [WMD=﹣4.65, 95%CI（﹣8.91, ﹣0.38）,P=0.03].CONCLUSION： TCM has potential positive effects in the treatment of influenza.
ISSN:0255-2922