H3K4me3 epigenomic landscape derived from ChIP-Seq of 1000 mouse early embryonic cells

Dear Editor, Epigenetic regulation is crucial to the establishment and maintenance of the identity of a cell. Recent stud- ies suggest that transcription is implemented amongst a mixture of various histone modifications [1]. It has also been recognized that to interrogate function of genetic informa...

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Bibliographic Details
Published in:细胞研究：英文版 2015 (1), p.143-147
Main Author: Jie Shen Dongqing Jiang Yusi Fu Xinglong Wu Hongshan Guo Binxiao Feng Yuhong Pang Aaron M Streets Fuchou Tang Yanyi Huang
Format: Article
Language:English
Subjects:
小鼠
早期
景观
组蛋白修饰
胚胎细胞
芯片
表观
遗传调控
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Summary:Dear Editor, Epigenetic regulation is crucial to the establishment and maintenance of the identity of a cell. Recent stud- ies suggest that transcription is implemented amongst a mixture of various histone modifications [1]. It has also been recognized that to interrogate function of genetic information, comprehensively systematic profiling of the epigenome in multiple cell stages and types is required [2].
ISSN:1001-0602
1748-7838