Staging systems for hepatocellular carcinoma： Currentstatus and future perspectives

Hepatocellular carcinoma （HCC） is a major healthconcern worldwide and the third cause of cancer-relateddeath. Despite advances in treatment as well as carefulsurveillance programs, the mortality rates in mostcountries are very high. In contrast to other cancers,the prognosis and treatment of HCC dep...

Full description

Saved in:
Bibliographic Details
Published in:世界肝病学杂志：英文版（电子版） 2015 (3), p.406-424
Main Author: Akiyoshi Kinoshita Hiroshi Onoda Nao Fushiya Kazuhiko Koike Hirokazu Nishino Hisao Tajiri
Format: Article
Language:English
Subjects:
carcinoma
Hepatocellular
Prognosis
Staging
system
system
Scoring
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hepatocellular carcinoma （HCC） is a major healthconcern worldwide and the third cause of cancer-relateddeath. Despite advances in treatment as well as carefulsurveillance programs, the mortality rates in mostcountries are very high. In contrast to other cancers,the prognosis and treatment of HCC depend on thetumor burden in addition to patient＇s underlying liverdisease and liver functional reserve. Moreover, thereis considerable geographic and institutional variationin both risk factors attributable to the underlying liverdiseases and the management of HCC. Therefore,although many staging and/or scoring systems havebeen proposed, there is currently no globally acceptedsystem for HCC due to the extreme heterogeneityof the disease. The aim of this review is to focus oncurrently available staging systems as well as thosenewly reported in the literatures since 2012. Moreover,we describe problems with currently available stagingsystems and attempts to modify and/or add variables toexisting staging systems.
ISSN:1948-5182
1948-5182