Brain metastasis in non-small cell lung cancer （NSCLC） patients with uncommon EGFR mutations： a report of seven cases and literature review

Brain metastasis （BM） arising from non-small cell lung cancer （NSCLC） with rare epidermal growth factor receptor （EGFR） mutations is quite rare. The prognosis and therapeutic effects of BM remain enigmatic. To the best of our knowledge, this is the first report to make a separate analysis of BM from...

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Bibliographic Details
Published in:癌症生物学与医学：英文版 2017, Vol.14 (4), p.418-425
Main Authors: Puchun Er, Tian Zhang, Jing Wang, Qingsong Pang, Ping Wang
Format: Article
Language:English
Online Access:Get full text
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Summary:Brain metastasis （BM） arising from non-small cell lung cancer （NSCLC） with rare epidermal growth factor receptor （EGFR） mutations is quite rare. The prognosis and therapeutic effects of BM remain enigmatic. To the best of our knowledge, this is the first report to make a separate analysis of BM from NSCLC patients with original uncommon EGFR mutations. We retrospectively reviewed 7 cases of BM arising from 42 cases of uncommon EGFR mutated lung cancer in Tianjin Medical University Cancer Institute and Hospital. We also t,erformed a literature review to assess therapeutic features and outcomes.
ISSN:2095-3941