Electromembrane extraction in microfluidic formats

Electromembrane extraction is a microextraction technique where charged analytes are extracted across a supported liquid membrane and selectively isolated from the sample based on an electrical field. Since the introduction in 2006, there has been continuously increasing interest in electromembrane...

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Bibliographic Details
Published in:Journal of separation science 2022-01, Vol.45 (1), p.246-257
Main Authors: Hansen, Frederik André, Petersen, Nickolaj Jacob, Kutter, Jörg P., Pedersen‐Bjergaard, Stig
Format: Article
Language:English
Subjects:
Beverages
electromembrane extraction
Liquid membranes
microextraction
Microfluidics
sample preparation
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Summary:Electromembrane extraction is a microextraction technique where charged analytes are extracted across a supported liquid membrane and selectively isolated from the sample based on an electrical field. Since the introduction in 2006, there has been continuously increasing interest in electromembrane extraction, and currently close to 50 new articles are published per year. Electromembrane extraction can be performed in different technical configurations, based on standard laboratory glass vials or 96‐well plate systems, and applications are typically related to pharmaceutical, environmental, and food and beverages analysis. In addition to this, conceptual research has developed electromembrane extraction into different milli‐ and microfluidic formats. These are much more early‐stage activities, but applications among others related to organ‐on‐chip systems and smartphone detection indicate unique perspectives. To stimulate more research in this direction, the current article reviews the scientific literature on electromembrane extraction in milli‐ and microfluidic formats. About 20 original research articles have been published on this subject so far, and these are discussed critically in the following. Based on this and the authors own experiences with the topic, we discuss perspectives, challenges, and future research.
ISSN:1615-9306
1615-9314
DOI:10.1002/jssc.202100603