Tobacco smoking related to childhood trauma mediated by cognitive control and impulsiveness in severe mental disorders

• Published in: Schizophrenia research 2023-11, Vol.261, p.236-244
• Main Authors: Lunding, Synve Hoffart, Ueland, Torill, Aas, Monica, Høegh, Margrethe Collier, Werner, Maren Caroline Frogner, Rødevand, Linn, Johansen, Ingrid Torp, Hjell, Gabriela, Ormerod, Monica Bettina Elkjær Greenwood, Ringen, Petter Andreas, Ottesen, Akiah, Lagerberg, Trine Vik, Melle, Ingrid, Andreassen, Ole A., Simonsen, Carmen, Steen, Nils Eiel
• Format: Article
• Language: English
• Subjects: Adult; Adverse Childhood Experiences; Bipolar Disorder - psychology; Bipolar disorders; Cognition; Humans; Nicotiana; Schizophrenia; Smoking - epidemiology; Tobacco Smoking
• ISSN: 0920-9964; 1573-2509
• DOI: 10.1016/j.schres.2023.09.041

People with severe mental disorders (SMDs) show an increased prevalence of tobacco smoking compared to the general population. Tobacco smoking and other adult adverse health behaviors have been associated with traumatic experiences in childhood. In the present study we investigated the relationship between childhood trauma and tobacco smoking in people with SMDs, including the possible mediating role of cognitive- and personality characteristics, i.e. cognitive control, impulsiveness, affective lability and self-esteem. Enrolled in the study were 871 participants with schizophrenia (SCZ, N = 484) and bipolar (BD, N = 387) spectrum disorders. We assessed tobacco smoking behavior (yes/no and amount), and history of childhood trauma with the Childhood Trauma Questionnaire. Data on cognitive control, impulsiveness, affective lability, and self-esteem were available in subsamples. We performed linear and logistic regressions, and conducted mediation analyses in PROCESS. All analyses were as standard adjusted for age, sex, and diagnostic group. Experience of one or more subtypes of childhood trauma was significantly associated with smoking tobacco in SMDs (p = 0.002). There were no significant associations between childhood trauma and amount of tobacco smoking. Cognitive control and impulsiveness were significant mediators between childhood trauma and tobacco smoking. These findings indicate the experience of childhood trauma as a predisposing factor for tobacco smoking in SMDs. Cognitive control and impulsiveness were suggested as mediating mechanisms, indicating the importance of considering inhibition related self-regulatory aspects in efforts to improve health behavior in individuals with SMDs and childhood trauma.