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Ocular findings in 87 adults with Ghent‐1 verified Marfan syndrome

Purpose To study ocular characteristics in 87 patients with verified Marfan syndrome (MFS) based on the Ghent criteria from 1996 (Ghent‐1). Methods The position of the lens was noted by observing the eye in different gaze directions in maximal mydriasis during slit lamp examination. Ectopia lentis (...

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Published in:Acta ophthalmologica (Oxford, England) England), 2015-02, Vol.93 (1), p.46-53
Main Authors: Drolsum, Liv, Rand‐Hendriksen, Svend, Paus, Benedicte, Geiran, Odd R., Semb, Svein Ove
Format: Article
Language:English
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Summary:Purpose To study ocular characteristics in 87 patients with verified Marfan syndrome (MFS) based on the Ghent criteria from 1996 (Ghent‐1). Methods The position of the lens was noted by observing the eye in different gaze directions in maximal mydriasis during slit lamp examination. Ectopia lentis (EL) was classified as subluxated (dislocation slightly backwards) or luxated (vertical or horizontal displacement). Corneal curvature, axial length (AL), corneal diameter, central corneal thickness, anterior chamber depth, lens thickness, condition of the iris, intraocular pressure, spherical equivalent and visual acuity were also investigated. Results EL was found in 108 eyes (62.1%). Of the 68 phakic eyes with EL, 43 (63.2%) had subluxation. Mean AL was 24.80 ± 2.57 mm, and the AL was above 23.5 mm in 65.3%. Mean keratometry (K) in phakic eyes was 41.79 ± 1.70 diopters (D), and the K value was
ISSN:1755-375X
1755-3768
DOI:10.1111/aos.12448