Erosive Esophagitis and Symptoms of Gastroesophageal Reflux Disease in Patients with Morbid Obesity with and without Type 2 Diabetes: a Cross-sectional Study

Background Type 2 diabetes (T2DM) is associated with gastroesophageal reflux disease (GERD) in the general population, but the relationship between these conditions in candidates for bariatric surgery is uncertain. We compared the prevalence of GERD and the association between GERD symptoms and esop...

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Bibliographic Details
Published in:Obesity surgery 2020-07, Vol.30 (7), p.2667-2675
Main Authors: Lorentzen, Jolanta, Medhus, Asle W., Hertel, Jens Kristoffer, Borgeraas, Heidi, Karlsen, Tor-Ivar, Kolotkin, Ronette L., Sandbu, Rune, Sifrim, Daniel, Svanevik, Marius, Hofsø, Dag, Seip, Birgitte, Hjelmesæth, Jøran
Format: Article
Language:English
Subjects:
Adult
Cross-Sectional Studies
Diabetes
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - epidemiology
Female
Gastroesophageal reflux
Gastroesophageal Reflux - complications
Gastroesophageal Reflux - epidemiology
Gastrointestinal surgery
Humans
Medicine
Medicine & Public Health
Middle Aged
Norway - epidemiology
Obesity, Morbid - surgery
Original Contributions
Surgery
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Summary:Background Type 2 diabetes (T2DM) is associated with gastroesophageal reflux disease (GERD) in the general population, but the relationship between these conditions in candidates for bariatric surgery is uncertain. We compared the prevalence of GERD and the association between GERD symptoms and esophagitis among bariatric candidates with and without T2DM. Methods Cross-sectional study of baseline data from the Oseberg study in Norway. Both groups underwent gastroduodenoscopy and completed validated questionnaires: Gastrointestinal Symptom Rating Scale and Gastroesophageal Reflux Disease Questionnaire. Participants with T2DM underwent 24-h pH-metry. Results A total of 124 patients with T2DM, 81 women, mean (SD) age 48.6 (9.4) years and BMI 42.3 (5.5) kg/m 2 , and 64 patients without T2DM, 46 women, age 43.0 (11.0) years and BMI 43.0 (5.0) kg/m 2 , were included. The proportions of patients reporting GERD-symptoms were low (
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-020-04545-w