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Severity of anabolic steroid dependence, executive function, and personality traits in substance use disorder patients in Norway
Anabolic androgenic steroids (AAS), including testosterone and synthetic derivatives, are typically used to increase muscle mass. Many users develop a dependence on these substances, contributing to worsened physical and mental health outcomes. Aspects of personality and executive dysfunction may re...
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Published in: | Drug and alcohol dependence 2022-02, Vol.231, p.109275-109275, Article 109275 |
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description | Anabolic androgenic steroids (AAS), including testosterone and synthetic derivatives, are typically used to increase muscle mass. Many users develop a dependence on these substances, contributing to worsened physical and mental health outcomes. Aspects of personality and executive dysfunction may represent underlying vulnerabilities for developing dependence.
To identify levels of AAS dependence within substance use disorder (SUD) treatment patients and assess the relationship between dependence severity and personality traits and executive function (EF).
Data were collected from patients at 38 SUD treatment facilities in Norway. Questionnaires were completed for measures of personality and EF. Measures of symptoms of AAS dependence were used in latent class analysis to identify sub-groups of patients, which were evaluated for association with EF and personality traits, and compared with a group of non-AAS using SUD patients.
Three classes were identified; largely reflecting low, moderate, and high symptoms of dependence. Multinomial regression analyses indicated that moderate and high symptoms were associated with several measures of EF and personality traits, particularly self-monitoring, antagonism, disinhibition, and rigid perfectionism while users with low symptoms exhibited higher capacities for emotional control and shift, and lower negative affectivity, relative to non-AAS using SUD patients. Backward stepwise regressions indicated antagonism, and decreased self-monitoring as key personality and cognitive characteristics of SUD patients with severe AAS dependence.
Our findings indicate that specific executive dysfunctions and personality features, particularly those associated with poor emotional control, reduced empathy, and impulsivity are associated with more severe AAS dependence in the SUD population.
•Three latent classes of anabolic androgenic steroid dependence were identified.•Classes largely reflected severity of dependence by number of symptoms reported.•High dependence is associated with worse self-monitoring and emotional control.•Antagonism was the strongest predictor of high dependence symptoms. |
doi_str_mv | 10.1016/j.drugalcdep.2022.109275 |
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To identify levels of AAS dependence within substance use disorder (SUD) treatment patients and assess the relationship between dependence severity and personality traits and executive function (EF).
Data were collected from patients at 38 SUD treatment facilities in Norway. Questionnaires were completed for measures of personality and EF. Measures of symptoms of AAS dependence were used in latent class analysis to identify sub-groups of patients, which were evaluated for association with EF and personality traits, and compared with a group of non-AAS using SUD patients.
Three classes were identified; largely reflecting low, moderate, and high symptoms of dependence. Multinomial regression analyses indicated that moderate and high symptoms were associated with several measures of EF and personality traits, particularly self-monitoring, antagonism, disinhibition, and rigid perfectionism while users with low symptoms exhibited higher capacities for emotional control and shift, and lower negative affectivity, relative to non-AAS using SUD patients. Backward stepwise regressions indicated antagonism, and decreased self-monitoring as key personality and cognitive characteristics of SUD patients with severe AAS dependence.
Our findings indicate that specific executive dysfunctions and personality features, particularly those associated with poor emotional control, reduced empathy, and impulsivity are associated with more severe AAS dependence in the SUD population.
•Three latent classes of anabolic androgenic steroid dependence were identified.•Classes largely reflected severity of dependence by number of symptoms reported.•High dependence is associated with worse self-monitoring and emotional control.•Antagonism was the strongest predictor of high dependence symptoms.</description><identifier>ISSN: 0376-8716</identifier><identifier>EISSN: 1879-0046</identifier><identifier>DOI: 10.1016/j.drugalcdep.2022.109275</identifier><identifier>PMID: 35030506</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Anabolic Agents - adverse effects ; Anabolic androgenic steroids ; Anabolic steroids ; Androgenic steroids ; Cognitive ability ; Disinhibition ; Drug addiction ; Drug use ; Emotions ; Empathy ; Executive Function ; Health status ; Hostility ; Humans ; Impulsive behavior ; Impulsivity ; Latent class analysis ; Medical treatment ; Mental health ; Monitoring ; Muscles ; Negative emotions ; Patients ; Perfectionism ; Personality ; Personality traits ; Regression analysis ; Selfmonitoring ; Severity ; Steroid hormones ; Steroids ; Substance use ; Substance use disorder ; Substance-Related Disorders - epidemiology ; Substance-Related Disorders - psychology ; Symptoms ; Telemedicine ; Testosterone ; Testosterone Congeners - adverse effects</subject><ispartof>Drug and alcohol dependence, 2022-02, Vol.231, p.109275-109275, Article 109275</ispartof><rights>2022 The Authors</rights><rights>Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.</rights><rights>Copyright Elsevier Science Ltd. Feb 1, 2022</rights><rights>info:eu-repo/semantics/openAccess</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c476t-47efe66249b49638c1293ecbbf03cf4a4dd50615729504d39ae9eca54cc1906f3</citedby><cites>FETCH-LOGICAL-c476t-47efe66249b49638c1293ecbbf03cf4a4dd50615729504d39ae9eca54cc1906f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0376871622000126$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,780,784,885,3549,26567,27924,27925,30999,45780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35030506$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Scarth, Morgan</creatorcontrib><creatorcontrib>Havnes, Ingrid A.</creatorcontrib><creatorcontrib>Jørstad, Marie L.</creatorcontrib><creatorcontrib>McVeigh, Jim</creatorcontrib><creatorcontrib>Van Hout, Marie Claire</creatorcontrib><creatorcontrib>Westlye, Lars T.</creatorcontrib><creatorcontrib>Torgersen, Svenn</creatorcontrib><creatorcontrib>Bjørnebekk, Astrid</creatorcontrib><title>Severity of anabolic steroid dependence, executive function, and personality traits in substance use disorder patients in Norway</title><title>Drug and alcohol dependence</title><addtitle>Drug Alcohol Depend</addtitle><description>Anabolic androgenic steroids (AAS), including testosterone and synthetic derivatives, are typically used to increase muscle mass. Many users develop a dependence on these substances, contributing to worsened physical and mental health outcomes. Aspects of personality and executive dysfunction may represent underlying vulnerabilities for developing dependence.
To identify levels of AAS dependence within substance use disorder (SUD) treatment patients and assess the relationship between dependence severity and personality traits and executive function (EF).
Data were collected from patients at 38 SUD treatment facilities in Norway. Questionnaires were completed for measures of personality and EF. Measures of symptoms of AAS dependence were used in latent class analysis to identify sub-groups of patients, which were evaluated for association with EF and personality traits, and compared with a group of non-AAS using SUD patients.
Three classes were identified; largely reflecting low, moderate, and high symptoms of dependence. Multinomial regression analyses indicated that moderate and high symptoms were associated with several measures of EF and personality traits, particularly self-monitoring, antagonism, disinhibition, and rigid perfectionism while users with low symptoms exhibited higher capacities for emotional control and shift, and lower negative affectivity, relative to non-AAS using SUD patients. Backward stepwise regressions indicated antagonism, and decreased self-monitoring as key personality and cognitive characteristics of SUD patients with severe AAS dependence.
Our findings indicate that specific executive dysfunctions and personality features, particularly those associated with poor emotional control, reduced empathy, and impulsivity are associated with more severe AAS dependence in the SUD population.
•Three latent classes of anabolic androgenic steroid dependence were identified.•Classes largely reflected severity of dependence by number of symptoms reported.•High dependence is associated with worse self-monitoring and emotional control.•Antagonism was the strongest predictor of high dependence symptoms.</description><subject>Anabolic Agents - adverse effects</subject><subject>Anabolic androgenic steroids</subject><subject>Anabolic steroids</subject><subject>Androgenic steroids</subject><subject>Cognitive ability</subject><subject>Disinhibition</subject><subject>Drug addiction</subject><subject>Drug use</subject><subject>Emotions</subject><subject>Empathy</subject><subject>Executive Function</subject><subject>Health status</subject><subject>Hostility</subject><subject>Humans</subject><subject>Impulsive behavior</subject><subject>Impulsivity</subject><subject>Latent class analysis</subject><subject>Medical treatment</subject><subject>Mental health</subject><subject>Monitoring</subject><subject>Muscles</subject><subject>Negative emotions</subject><subject>Patients</subject><subject>Perfectionism</subject><subject>Personality</subject><subject>Personality traits</subject><subject>Regression analysis</subject><subject>Selfmonitoring</subject><subject>Severity</subject><subject>Steroid hormones</subject><subject>Steroids</subject><subject>Substance use</subject><subject>Substance use disorder</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Substance-Related Disorders - psychology</subject><subject>Symptoms</subject><subject>Telemedicine</subject><subject>Testosterone</subject><subject>Testosterone Congeners - adverse effects</subject><issn>0376-8716</issn><issn>1879-0046</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><sourceid>3HK</sourceid><recordid>eNqFkU2P1SAUhhujca6jf0FJ3LiYXvkqlKVO_EomulDXhMKp4aYXKtCrd-dPl6YzmriRDQl53vOG8zQNInhPMBEvD3uXlm9msg7mPcWU1mdFZXev2ZFeqhZjLu43O8ykaHtJxEXzKOcDrkco_LC5YB1muMNi1_z6DCdIvpxRHJEJZoiTtygXSNE7VMdDcBAsXCH4CXYp_gRoXIItPoarGnBohpRjMNM6oyTjS0Y-oLwMuZgaREsG5HyOyUFCsykewoZ8jOmHOT9uHoxmyvDk9r5svr598-X6fXvz6d2H61c3reVSlJZLGEEIytXAlWC9JVQxsMMwYmZHbrhz9T-kk1R1mDumDCiwpuPWEoXFyC6bZ9tcm3wuPugQk9EE9x3VStaOSrzYiDnF7wvkoo8-W5gmEyAuWVNBMe6Z7GVFn_-DHuKS6hJWivW4p5ySSvV3lTHnBKOekz-adK61evWoD_qvR7161JvHGn16W7AMR3B_gnfiKvB6A6Du7OQh6Wz9Ksr5BLZoF_3_W34DmtC0DQ</recordid><startdate>20220201</startdate><enddate>20220201</enddate><creator>Scarth, Morgan</creator><creator>Havnes, Ingrid A.</creator><creator>Jørstad, Marie L.</creator><creator>McVeigh, Jim</creator><creator>Van Hout, Marie Claire</creator><creator>Westlye, Lars T.</creator><creator>Torgersen, Svenn</creator><creator>Bjørnebekk, Astrid</creator><general>Elsevier B.V</general><general>Elsevier Science Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>3HK</scope></search><sort><creationdate>20220201</creationdate><title>Severity of anabolic steroid dependence, executive function, and personality traits in substance use disorder patients in Norway</title><author>Scarth, Morgan ; Havnes, Ingrid A. ; Jørstad, Marie L. ; McVeigh, Jim ; Van Hout, Marie Claire ; Westlye, Lars T. ; Torgersen, Svenn ; Bjørnebekk, Astrid</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c476t-47efe66249b49638c1293ecbbf03cf4a4dd50615729504d39ae9eca54cc1906f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Anabolic Agents - adverse effects</topic><topic>Anabolic androgenic steroids</topic><topic>Anabolic steroids</topic><topic>Androgenic steroids</topic><topic>Cognitive ability</topic><topic>Disinhibition</topic><topic>Drug addiction</topic><topic>Drug use</topic><topic>Emotions</topic><topic>Empathy</topic><topic>Executive Function</topic><topic>Health status</topic><topic>Hostility</topic><topic>Humans</topic><topic>Impulsive behavior</topic><topic>Impulsivity</topic><topic>Latent class analysis</topic><topic>Medical treatment</topic><topic>Mental health</topic><topic>Monitoring</topic><topic>Muscles</topic><topic>Negative emotions</topic><topic>Patients</topic><topic>Perfectionism</topic><topic>Personality</topic><topic>Personality traits</topic><topic>Regression analysis</topic><topic>Selfmonitoring</topic><topic>Severity</topic><topic>Steroid hormones</topic><topic>Steroids</topic><topic>Substance use</topic><topic>Substance use disorder</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Substance-Related Disorders - psychology</topic><topic>Symptoms</topic><topic>Telemedicine</topic><topic>Testosterone</topic><topic>Testosterone Congeners - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scarth, Morgan</creatorcontrib><creatorcontrib>Havnes, Ingrid A.</creatorcontrib><creatorcontrib>Jørstad, Marie L.</creatorcontrib><creatorcontrib>McVeigh, Jim</creatorcontrib><creatorcontrib>Van Hout, Marie Claire</creatorcontrib><creatorcontrib>Westlye, Lars T.</creatorcontrib><creatorcontrib>Torgersen, Svenn</creatorcontrib><creatorcontrib>Bjørnebekk, Astrid</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>NORA - Norwegian Open Research Archives</collection><jtitle>Drug and alcohol dependence</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Scarth, Morgan</au><au>Havnes, Ingrid A.</au><au>Jørstad, Marie L.</au><au>McVeigh, Jim</au><au>Van Hout, Marie Claire</au><au>Westlye, Lars T.</au><au>Torgersen, Svenn</au><au>Bjørnebekk, Astrid</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Severity of anabolic steroid dependence, executive function, and personality traits in substance use disorder patients in Norway</atitle><jtitle>Drug and alcohol dependence</jtitle><addtitle>Drug Alcohol Depend</addtitle><date>2022-02-01</date><risdate>2022</risdate><volume>231</volume><spage>109275</spage><epage>109275</epage><pages>109275-109275</pages><artnum>109275</artnum><issn>0376-8716</issn><eissn>1879-0046</eissn><abstract>Anabolic androgenic steroids (AAS), including testosterone and synthetic derivatives, are typically used to increase muscle mass. Many users develop a dependence on these substances, contributing to worsened physical and mental health outcomes. Aspects of personality and executive dysfunction may represent underlying vulnerabilities for developing dependence.
To identify levels of AAS dependence within substance use disorder (SUD) treatment patients and assess the relationship between dependence severity and personality traits and executive function (EF).
Data were collected from patients at 38 SUD treatment facilities in Norway. Questionnaires were completed for measures of personality and EF. Measures of symptoms of AAS dependence were used in latent class analysis to identify sub-groups of patients, which were evaluated for association with EF and personality traits, and compared with a group of non-AAS using SUD patients.
Three classes were identified; largely reflecting low, moderate, and high symptoms of dependence. Multinomial regression analyses indicated that moderate and high symptoms were associated with several measures of EF and personality traits, particularly self-monitoring, antagonism, disinhibition, and rigid perfectionism while users with low symptoms exhibited higher capacities for emotional control and shift, and lower negative affectivity, relative to non-AAS using SUD patients. Backward stepwise regressions indicated antagonism, and decreased self-monitoring as key personality and cognitive characteristics of SUD patients with severe AAS dependence.
Our findings indicate that specific executive dysfunctions and personality features, particularly those associated with poor emotional control, reduced empathy, and impulsivity are associated with more severe AAS dependence in the SUD population.
•Three latent classes of anabolic androgenic steroid dependence were identified.•Classes largely reflected severity of dependence by number of symptoms reported.•High dependence is associated with worse self-monitoring and emotional control.•Antagonism was the strongest predictor of high dependence symptoms.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>35030506</pmid><doi>10.1016/j.drugalcdep.2022.109275</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Anabolic Agents - adverse effects Anabolic androgenic steroids Anabolic steroids Androgenic steroids Cognitive ability Disinhibition Drug addiction Drug use Emotions Empathy Executive Function Health status Hostility Humans Impulsive behavior Impulsivity Latent class analysis Medical treatment Mental health Monitoring Muscles Negative emotions Patients Perfectionism Personality Personality traits Regression analysis Selfmonitoring Severity Steroid hormones Steroids Substance use Substance use disorder Substance-Related Disorders - epidemiology Substance-Related Disorders - psychology Symptoms Telemedicine Testosterone Testosterone Congeners - adverse effects |
title | Severity of anabolic steroid dependence, executive function, and personality traits in substance use disorder patients in Norway |
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