Laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma: a multicenter propensity score-matched study

Background The role of laparoscopy in the treatment of intrahepatic cholangiocarcinoma (ICC) remains unclear. This multicenter study examined the outcomes of laparoscopic liver resection for ICC. Methods Patients with ICC who had undergone laparoscopic or open liver resection between 2012 and 2019 a...

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Published in:Scandinavian journal of gastroenterology 2022
Main Authors: Sahakyan, Mushegh, Aghayan, Davit, Edwin, Bjørn von Gohren, Alikhanov, Ruslan, Britskaia, Natalia, Brudvik, Kristoffer Watten, D’Hondt, Mathieu, De Meyere, Celine, Efanov, Mikhail, Fretland, Åsmund Avdem, Hoff, Rune, Ismail, Warsan, Ivanecz, Arpad, Kazaryan, Airazat, Lassen, Kristoffer, Magdalenić, Tomislav, Parmentier, Isabelle, Røsok, Bård Ingvald, Villanger, Olaug, Yaqub, Sheraz
Format: Article
Language:Norwegian
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Summary:Background The role of laparoscopy in the treatment of intrahepatic cholangiocarcinoma (ICC) remains unclear. This multicenter study examined the outcomes of laparoscopic liver resection for ICC. Methods Patients with ICC who had undergone laparoscopic or open liver resection between 2012 and 2019 at four European expert centers were included in the study. Laparoscopic and open approaches were compared in terms of surgical and oncological outcomes. Propensity score matching was used for minimizing treatment selection bias and adjusting for confounders (age, ASA grade, tumor size, location, number of tumors and underlying liver disease). Results Of 136 patients, 50 (36.7%) underwent laparoscopic resection, whereas 86 (63.3%) had open surgery. Median tumor size was larger (73.6 vs 55.1 mm, p = 0.01) and the incidence of bi-lobar tumors was higher (36.6 vs 6%, p 
ISSN:0036-5521
1502-7708