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Raman and Infrared spectroscopies and X-ray diffraction data on bupivacaine and ropivacaine complexed with 2-hydroxypropyl-beta-cyclodextrin

The data presented in this article are related to the research article entitled “Probing the dynamics of complexed local anesthetics via neutron scattering spectroscopy and DFT calculations (http://dx.doi.org/10.1016/j.ijpharm.2017.03.051)” (Martins et al., 2017) [1]. This work shows the molecular a...

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Main Authors: Martins, Murillo L, Eckert, Jürgen, Jacobsen, Henrik, Dos Santos, Éverton Carvalho, Ignazzi, Rosanna, de Araujo, Daniele Ribeiro, Bellissent-Funel, Marie-Claire, Natali, Francesca, Marek Koza, Michael, Matic, Aleksander, de Paula, Eneida, Bordallo, Heloisa N
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Language:English
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Summary:The data presented in this article are related to the research article entitled “Probing the dynamics of complexed local anesthetics via neutron scattering spectroscopy and DFT calculations (http://dx.doi.org/10.1016/j.ijpharm.2017.03.051)” (Martins et al., 2017) [1]. This work shows the molecular and structural behavior of the local anesthetics (LAs) bupivacaine (BVC, C18H28N2O) and ropivacaine (RVC, C17H26N2O) before and after complexation with the water-soluble oligosaccharide 2-hydroxypropyl−β−cyclodextrin (HP-β-CD).