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The Effect of Smoking on Long-term Gray Matter Atrophy and Clinical Disability in Patients with Relapsing-Remitting Multiple Sclerosis

The relationship between smoking, long-term brain atrophy, and clinical disability in patients with multiple sclerosis (MS) is unclear. Here, we assessed long-term effects of smoking by evaluating MRI and clinical outcome measures after 10 years in smoking and nonsmoking patients with relapsing-remi...

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Main Authors: Lie, Ingrid Anne, Wesnes, Kristin, Kvistad, Silje S, Brouwer, Iman, Wergeland, Stig, Holmøy, Trygve, Midgard, Rune, Bru, Alla Nikolajevna S, Edland, Astrid, Eikeland, Randi, Gosal, Sonia, Harbo, Hanne-Cathrin Flinstad, Kleveland, Grethe, Sørenes, Yvonne, Øksendal, Nina, Barkhof, Frederik, Vrenken, Hugo, Myhr, Kjell-Morten, Bø, Lars, Torkildesen, Øivind
Format: Article
Language:English
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Summary:The relationship between smoking, long-term brain atrophy, and clinical disability in patients with multiple sclerosis (MS) is unclear. Here, we assessed long-term effects of smoking by evaluating MRI and clinical outcome measures after 10 years in smoking and nonsmoking patients with relapsing-remitting MS (RRMS).