Perfusion estimation using synthetic MRI-based measurements and a porous media flow model

The measurement of perfusion and filtration of blood in biological tissue give rise to important clinical parameters used in diagnosis, follow-up, and therapy. In this paper, we address techniques for perfusion analysis using processed contrast agent concentration data from dynamic MRI acquisitions....

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Main Authors: Lorentzen, Rolf Johan, Nævdal, Geir, Sævareid, Ove, Hodneland, Erlend, Hanson, Erik Andreas, Munthe-Kaas, Antonella Zanna
Format: Article
Language:English
Online Access:Request full text
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Summary:The measurement of perfusion and filtration of blood in biological tissue give rise to important clinical parameters used in diagnosis, follow-up, and therapy. In this paper, we address techniques for perfusion analysis using processed contrast agent concentration data from dynamic MRI acquisitions. A new methodology for analysis is evaluated and verified using synthetic data generated on a tissue geometry.