Time analysis of alveolar ridge preservation using a combination of mineralized bone‐plug and dense‐polytetrafluoroethylene membrane: A histomorphometric study

Background The objective of this study was to histologically evaluate and compare vital bone formation, residual graft particles, and fraction of connective tissue (CT)/other tissues between three different time points at 2‐month intervals after alveolar ridge preservation with a cancellous allograf...

Full description

Saved in:
Bibliographic Details
Published in:Journal of periodontology (1970) 2020-02, Vol.91 (2), p.215-222
Main Authors: Wen, Shih‐Cheng, Barootchi, Shayan, Huang, Wen‐Xia, Wang, Hom‐Lay
Format: Article
Language:English
Subjects:
allografts
alveolar bone loss
alveolar resorption
bone transplantation
polytetrafluoroethylene
socket graft
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c3405-2f5da839b88563595f658528ce0d2b6d89d740360149a6846e935212ad2013c53
cites cdi_FETCH-LOGICAL-c3405-2f5da839b88563595f658528ce0d2b6d89d740360149a6846e935212ad2013c53
container_end_page 222
container_issue 2
container_start_page 215
container_title Journal of periodontology (1970)
container_volume 91
creator Wen, Shih‐Cheng
Barootchi, Shayan
Huang, Wen‐Xia
Wang, Hom‐Lay
description Background The objective of this study was to histologically evaluate and compare vital bone formation, residual graft particles, and fraction of connective tissue (CT)/other tissues between three different time points at 2‐month intervals after alveolar ridge preservation with a cancellous allograft and dense‒polytetrafluoroethylene (d‐PTFE) membrane. Methods Ridge preservation with a cancellous allograft and d‐PTFE membrane was performed at 49 extraction sockets (one per patient). Volunteers were assigned to implant placement at three different time points of 2, 4, and 6 months, at which time core biopsies were obtained. Histomorphometric analysis was performed to determine the percentages of vital bone, residual graft particles, and connective tissue/other non‐bone components, and subjected to statistical analyses. Results There was a statistically significant difference in the amount of vital bone at every time point from 28.31% to 40.87% to 64.11% (at 2‐, 4‐, and 6‐month groups, respectively) (P 
doi_str_mv 10.1002/JPER.19-0142
format article
fullrecord <record><control><sourceid>wiley_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1002_JPER_19_0142</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JPER10405</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3405-2f5da839b88563595f658528ce0d2b6d89d740360149a6846e935212ad2013c53</originalsourceid><addsrcrecordid>eNp9kM1O3DAQxy0EKlvaG2fkB2ioP-Js3BtC0A-tBEL0HDnxhDXyR2QnoHDqI_Qd-mZ9Ery7wJHT6D_zm5Hmh9AxJaeUEPb11_XFzSmVBaEl20MLKkte8GpJ9tEij1nBS8kO0ceU7nOkJScf0CGnfFlLxhfo361xgJVXdk4m4dBjZR8gWBVxNPoO8BAhQXxQowkeT8n4O6xwF1xr_K6XV5zxEJU1T6BxGzz8__N3sFMGvcYafNo2gp1HGKPq7RRigHE9W_CAHbg2Kg_f8BlemzQGF-KwDi6jpsNpnPT8CR30yib4_FKP0O_Li9vzH8Xq6vvP87NV0fGSiIL1Qquay7auRcWFFH0lasHqDohmbaVrqZcl4VUWJVVVlxVILhhlSjNCeSf4Efqyu9vFkFKEvhmicSrODSXNxnWzcd1Q2WxcZ_xkhw9T60C_wa9yM8B3wKOxML97bBsoyW_wZ1UKjx0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Time analysis of alveolar ridge preservation using a combination of mineralized bone‐plug and dense‐polytetrafluoroethylene membrane: A histomorphometric study</title><source>Wiley</source><creator>Wen, Shih‐Cheng ; Barootchi, Shayan ; Huang, Wen‐Xia ; Wang, Hom‐Lay</creator><creatorcontrib>Wen, Shih‐Cheng ; Barootchi, Shayan ; Huang, Wen‐Xia ; Wang, Hom‐Lay</creatorcontrib><description>Background The objective of this study was to histologically evaluate and compare vital bone formation, residual graft particles, and fraction of connective tissue (CT)/other tissues between three different time points at 2‐month intervals after alveolar ridge preservation with a cancellous allograft and dense‒polytetrafluoroethylene (d‐PTFE) membrane. Methods Ridge preservation with a cancellous allograft and d‐PTFE membrane was performed at 49 extraction sockets (one per patient). Volunteers were assigned to implant placement at three different time points of 2, 4, and 6 months, at which time core biopsies were obtained. Histomorphometric analysis was performed to determine the percentages of vital bone, residual graft particles, and connective tissue/other non‐bone components, and subjected to statistical analyses. Results There was a statistically significant difference in the amount of vital bone at every time point from 28.31% to 40.87% to 64.11% (at 2‐, 4‐, and 6‐month groups, respectively) (P &lt; 0.05). The percentage of residual graft particles ranged from 44.57% to 36.16% to 14.86%, showing statistical significance from 4 to 6 months (21.29%, P &lt; 0.001), and 2 to 6 months (29.71%, P &lt; 0.001), while there were no significant differences for the amount of CT/other tissue among the different time points. Conclusions This study provided the first histologic comparison of alveolar ridge preservation using a cancellous allograft and d‐PTFE membrane at three different time points. Extraction sockets that healed for 6 months produced the highest amount of vital bone in combination with the least percentage of residual graft particles, while similar results were observed for the fraction of CT/other tissues between the three time points.</description><identifier>ISSN: 0022-3492</identifier><identifier>EISSN: 1943-3670</identifier><identifier>DOI: 10.1002/JPER.19-0142</identifier><identifier>PMID: 31378923</identifier><language>eng</language><publisher>United States</publisher><subject>allografts ; alveolar bone loss ; alveolar resorption ; bone transplantation ; polytetrafluoroethylene ; socket graft</subject><ispartof>Journal of periodontology (1970), 2020-02, Vol.91 (2), p.215-222</ispartof><rights>2019 American Academy of Periodontology</rights><rights>2019 American Academy of Periodontology.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3405-2f5da839b88563595f658528ce0d2b6d89d740360149a6846e935212ad2013c53</citedby><cites>FETCH-LOGICAL-c3405-2f5da839b88563595f658528ce0d2b6d89d740360149a6846e935212ad2013c53</cites><orcidid>0000-0003-4238-1799 ; 0000-0002-5347-6577</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31378923$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wen, Shih‐Cheng</creatorcontrib><creatorcontrib>Barootchi, Shayan</creatorcontrib><creatorcontrib>Huang, Wen‐Xia</creatorcontrib><creatorcontrib>Wang, Hom‐Lay</creatorcontrib><title>Time analysis of alveolar ridge preservation using a combination of mineralized bone‐plug and dense‐polytetrafluoroethylene membrane: A histomorphometric study</title><title>Journal of periodontology (1970)</title><addtitle>J Periodontol</addtitle><description>Background The objective of this study was to histologically evaluate and compare vital bone formation, residual graft particles, and fraction of connective tissue (CT)/other tissues between three different time points at 2‐month intervals after alveolar ridge preservation with a cancellous allograft and dense‒polytetrafluoroethylene (d‐PTFE) membrane. Methods Ridge preservation with a cancellous allograft and d‐PTFE membrane was performed at 49 extraction sockets (one per patient). Volunteers were assigned to implant placement at three different time points of 2, 4, and 6 months, at which time core biopsies were obtained. Histomorphometric analysis was performed to determine the percentages of vital bone, residual graft particles, and connective tissue/other non‐bone components, and subjected to statistical analyses. Results There was a statistically significant difference in the amount of vital bone at every time point from 28.31% to 40.87% to 64.11% (at 2‐, 4‐, and 6‐month groups, respectively) (P &lt; 0.05). The percentage of residual graft particles ranged from 44.57% to 36.16% to 14.86%, showing statistical significance from 4 to 6 months (21.29%, P &lt; 0.001), and 2 to 6 months (29.71%, P &lt; 0.001), while there were no significant differences for the amount of CT/other tissue among the different time points. Conclusions This study provided the first histologic comparison of alveolar ridge preservation using a cancellous allograft and d‐PTFE membrane at three different time points. Extraction sockets that healed for 6 months produced the highest amount of vital bone in combination with the least percentage of residual graft particles, while similar results were observed for the fraction of CT/other tissues between the three time points.</description><subject>allografts</subject><subject>alveolar bone loss</subject><subject>alveolar resorption</subject><subject>bone transplantation</subject><subject>polytetrafluoroethylene</subject><subject>socket graft</subject><issn>0022-3492</issn><issn>1943-3670</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kM1O3DAQxy0EKlvaG2fkB2ioP-Js3BtC0A-tBEL0HDnxhDXyR2QnoHDqI_Qd-mZ9Ery7wJHT6D_zm5Hmh9AxJaeUEPb11_XFzSmVBaEl20MLKkte8GpJ9tEij1nBS8kO0ceU7nOkJScf0CGnfFlLxhfo361xgJVXdk4m4dBjZR8gWBVxNPoO8BAhQXxQowkeT8n4O6xwF1xr_K6XV5zxEJU1T6BxGzz8__N3sFMGvcYafNo2gp1HGKPq7RRigHE9W_CAHbg2Kg_f8BlemzQGF-KwDi6jpsNpnPT8CR30yib4_FKP0O_Li9vzH8Xq6vvP87NV0fGSiIL1Qquay7auRcWFFH0lasHqDohmbaVrqZcl4VUWJVVVlxVILhhlSjNCeSf4Efqyu9vFkFKEvhmicSrODSXNxnWzcd1Q2WxcZ_xkhw9T60C_wa9yM8B3wKOxML97bBsoyW_wZ1UKjx0</recordid><startdate>202002</startdate><enddate>202002</enddate><creator>Wen, Shih‐Cheng</creator><creator>Barootchi, Shayan</creator><creator>Huang, Wen‐Xia</creator><creator>Wang, Hom‐Lay</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0003-4238-1799</orcidid><orcidid>https://orcid.org/0000-0002-5347-6577</orcidid></search><sort><creationdate>202002</creationdate><title>Time analysis of alveolar ridge preservation using a combination of mineralized bone‐plug and dense‐polytetrafluoroethylene membrane: A histomorphometric study</title><author>Wen, Shih‐Cheng ; Barootchi, Shayan ; Huang, Wen‐Xia ; Wang, Hom‐Lay</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3405-2f5da839b88563595f658528ce0d2b6d89d740360149a6846e935212ad2013c53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>allografts</topic><topic>alveolar bone loss</topic><topic>alveolar resorption</topic><topic>bone transplantation</topic><topic>polytetrafluoroethylene</topic><topic>socket graft</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wen, Shih‐Cheng</creatorcontrib><creatorcontrib>Barootchi, Shayan</creatorcontrib><creatorcontrib>Huang, Wen‐Xia</creatorcontrib><creatorcontrib>Wang, Hom‐Lay</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of periodontology (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wen, Shih‐Cheng</au><au>Barootchi, Shayan</au><au>Huang, Wen‐Xia</au><au>Wang, Hom‐Lay</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Time analysis of alveolar ridge preservation using a combination of mineralized bone‐plug and dense‐polytetrafluoroethylene membrane: A histomorphometric study</atitle><jtitle>Journal of periodontology (1970)</jtitle><addtitle>J Periodontol</addtitle><date>2020-02</date><risdate>2020</risdate><volume>91</volume><issue>2</issue><spage>215</spage><epage>222</epage><pages>215-222</pages><issn>0022-3492</issn><eissn>1943-3670</eissn><abstract>Background The objective of this study was to histologically evaluate and compare vital bone formation, residual graft particles, and fraction of connective tissue (CT)/other tissues between three different time points at 2‐month intervals after alveolar ridge preservation with a cancellous allograft and dense‒polytetrafluoroethylene (d‐PTFE) membrane. Methods Ridge preservation with a cancellous allograft and d‐PTFE membrane was performed at 49 extraction sockets (one per patient). Volunteers were assigned to implant placement at three different time points of 2, 4, and 6 months, at which time core biopsies were obtained. Histomorphometric analysis was performed to determine the percentages of vital bone, residual graft particles, and connective tissue/other non‐bone components, and subjected to statistical analyses. Results There was a statistically significant difference in the amount of vital bone at every time point from 28.31% to 40.87% to 64.11% (at 2‐, 4‐, and 6‐month groups, respectively) (P &lt; 0.05). The percentage of residual graft particles ranged from 44.57% to 36.16% to 14.86%, showing statistical significance from 4 to 6 months (21.29%, P &lt; 0.001), and 2 to 6 months (29.71%, P &lt; 0.001), while there were no significant differences for the amount of CT/other tissue among the different time points. Conclusions This study provided the first histologic comparison of alveolar ridge preservation using a cancellous allograft and d‐PTFE membrane at three different time points. Extraction sockets that healed for 6 months produced the highest amount of vital bone in combination with the least percentage of residual graft particles, while similar results were observed for the fraction of CT/other tissues between the three time points.</abstract><cop>United States</cop><pmid>31378923</pmid><doi>10.1002/JPER.19-0142</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-4238-1799</orcidid><orcidid>https://orcid.org/0000-0002-5347-6577</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0022-3492
ispartof Journal of periodontology (1970), 2020-02, Vol.91 (2), p.215-222
issn 0022-3492
1943-3670
language eng
recordid cdi_crossref_primary_10_1002_JPER_19_0142
source Wiley
subjects allografts
alveolar bone loss
alveolar resorption
bone transplantation
polytetrafluoroethylene
socket graft
title Time analysis of alveolar ridge preservation using a combination of mineralized bone‐plug and dense‐polytetrafluoroethylene membrane: A histomorphometric study
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T13%3A46%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wiley_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Time%20analysis%20of%20alveolar%20ridge%20preservation%20using%20a%20combination%20of%20mineralized%20bone%E2%80%90plug%20and%20dense%E2%80%90polytetrafluoroethylene%20membrane:%20A%20histomorphometric%20study&rft.jtitle=Journal%20of%20periodontology%20(1970)&rft.au=Wen,%20Shih%E2%80%90Cheng&rft.date=2020-02&rft.volume=91&rft.issue=2&rft.spage=215&rft.epage=222&rft.pages=215-222&rft.issn=0022-3492&rft.eissn=1943-3670&rft_id=info:doi/10.1002/JPER.19-0142&rft_dat=%3Cwiley_cross%3EJPER10405%3C/wiley_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3405-2f5da839b88563595f658528ce0d2b6d89d740360149a6846e935212ad2013c53%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/31378923&rfr_iscdi=true