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Photonic Crystals in Bioassays

Photonic crystal (PC) based bioassay techniques have many advantages in sensitive biomolecular screening, label‐free detection, real‐time monitoring of enzyme activity, cell morphology research, and so on. This study provides an overall survey of the basic concepts and up‐to‐date research concerning...

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Bibliographic Details
Published in:Advanced functional materials 2010-09, Vol.20 (18), p.2970-2988
Main Authors: Zhao, Yuanjin, Zhao, Xiangwei, Gu, Zhongze
Format: Article
Language:English
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Summary:Photonic crystal (PC) based bioassay techniques have many advantages in sensitive biomolecular screening, label‐free detection, real‐time monitoring of enzyme activity, cell morphology research, and so on. This study provides an overall survey of the basic concepts and up‐to‐date research concerning the very promising use of PC materials for bioassays. It includes the design and application of PC films, PC microcarriers, PC fibers, and PC optofluidics for fluorescence enhancement or label‐free bioassays. Emphasis is given to the description of the functional structures of different PC materials and their respective sensing mechanisms. Examples of detecting various types of analytes are presented. This article promotes communication among chemistry, biology, medicine, pharmacy, and material science. Photonic crystal (PC) based bioassay techniques have many advantages in sensitive biomolecular screening, label‐free detection, real‐time monitoring of enzyme activity, cell morphology research, and so on. This study provides an overall survey of the basic concepts and up‐to‐date research concerning the very promising use of the PC films, PC microcarriers, PC fibers, and PC optofluidics for bioassays.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.201000098