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Fibrous Viscoelastic Extracellular Matrix Assists Precise Neuronal Connectivity (Adv. Funct. Mater. 36/2023)
Axon Pathfinding In article number 2301926, Qihui Fan, Fangfu Ye, and co‐workers show that the mechanical signals transmitted through the fibrous extracellular matrix enable precise guidance of axons and neuronal cells towards target neurites, leading to highly efficient neural network formation. Th...
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Published in: | Advanced functional materials 2023-09, Vol.33 (36), p.n/a |
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container_title | Advanced functional materials |
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creator | Xie, Ruipei Yu, Xiaoyu Cao, Ting Yang, Chen Zhang, Yiyu Wang, Xiaochen Liu, Yi‐Jun Duan, Shumin Ye, Fangfu Fan, Qihui |
description | Axon Pathfinding
In article number 2301926, Qihui Fan, Fangfu Ye, and co‐workers show that the mechanical signals transmitted through the fibrous extracellular matrix enable precise guidance of axons and neuronal cells towards target neurites, leading to highly efficient neural network formation. This precise axon guidance mechanism is associated with the activation of mechanosensitive ion channels, calcium signals, and subsequent F‐actin assembly. |
doi_str_mv | 10.1002/adfm.202370217 |
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In article number 2301926, Qihui Fan, Fangfu Ye, and co‐workers show that the mechanical signals transmitted through the fibrous extracellular matrix enable precise guidance of axons and neuronal cells towards target neurites, leading to highly efficient neural network formation. This precise axon guidance mechanism is associated with the activation of mechanosensitive ion channels, calcium signals, and subsequent F‐actin assembly.</description><subject>axon pathfinding</subject><subject>extracellular matrix</subject><subject>mechanical signals</subject><subject>synapse formation</subject><issn>1616-301X</issn><issn>1616-3028</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqFkD1PwzAQhi0EEqWwMnuEIanPduNkjEoDSC0wAGKLHNeWjNwE2U4__j1ERWVkubvhnlevHoSugaRACJ3IlVmnlFAmCAVxgkaQQZYwQvPT4w0f5-gihE9CQAjGR8hVtvFdH_C7DarTToZoFZ7vopdKO9c76fFSRm93uAzBhhjwi9fKBo2fdO-7Vjo869pWq2g3Nu7xTbnapLjqWxXTgdQ-xSybDL1uL9GZkS7oq989Rm_V_HX2kCye7x9n5SJRQAuRcGqImhbaNHqV0ylwmRPOFYCSlENuRKOZyDIj8oYWU0YUbdQwJQWZC07ZGKWHXOW7ELw29Ze3a-n3NZB6cFUPruqjqx-gOABb6_T-n--6vKuWf-w3WT9tBQ</recordid><startdate>20230905</startdate><enddate>20230905</enddate><creator>Xie, Ruipei</creator><creator>Yu, Xiaoyu</creator><creator>Cao, Ting</creator><creator>Yang, Chen</creator><creator>Zhang, Yiyu</creator><creator>Wang, Xiaochen</creator><creator>Liu, Yi‐Jun</creator><creator>Duan, Shumin</creator><creator>Ye, Fangfu</creator><creator>Fan, Qihui</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20230905</creationdate><title>Fibrous Viscoelastic Extracellular Matrix Assists Precise Neuronal Connectivity (Adv. Funct. Mater. 36/2023)</title><author>Xie, Ruipei ; Yu, Xiaoyu ; Cao, Ting ; Yang, Chen ; Zhang, Yiyu ; Wang, Xiaochen ; Liu, Yi‐Jun ; Duan, Shumin ; Ye, Fangfu ; Fan, Qihui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1297-42f0c59efbed82514a8044c11ca2418f7be3766f78b29530c2bc30c2a21a87423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>axon pathfinding</topic><topic>extracellular matrix</topic><topic>mechanical signals</topic><topic>synapse formation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xie, Ruipei</creatorcontrib><creatorcontrib>Yu, Xiaoyu</creatorcontrib><creatorcontrib>Cao, Ting</creatorcontrib><creatorcontrib>Yang, Chen</creatorcontrib><creatorcontrib>Zhang, Yiyu</creatorcontrib><creatorcontrib>Wang, Xiaochen</creatorcontrib><creatorcontrib>Liu, Yi‐Jun</creatorcontrib><creatorcontrib>Duan, Shumin</creatorcontrib><creatorcontrib>Ye, Fangfu</creatorcontrib><creatorcontrib>Fan, Qihui</creatorcontrib><collection>CrossRef</collection><jtitle>Advanced functional materials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xie, Ruipei</au><au>Yu, Xiaoyu</au><au>Cao, Ting</au><au>Yang, Chen</au><au>Zhang, Yiyu</au><au>Wang, Xiaochen</au><au>Liu, Yi‐Jun</au><au>Duan, Shumin</au><au>Ye, Fangfu</au><au>Fan, Qihui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fibrous Viscoelastic Extracellular Matrix Assists Precise Neuronal Connectivity (Adv. Funct. Mater. 36/2023)</atitle><jtitle>Advanced functional materials</jtitle><date>2023-09-05</date><risdate>2023</risdate><volume>33</volume><issue>36</issue><epage>n/a</epage><issn>1616-301X</issn><eissn>1616-3028</eissn><abstract>Axon Pathfinding
In article number 2301926, Qihui Fan, Fangfu Ye, and co‐workers show that the mechanical signals transmitted through the fibrous extracellular matrix enable precise guidance of axons and neuronal cells towards target neurites, leading to highly efficient neural network formation. This precise axon guidance mechanism is associated with the activation of mechanosensitive ion channels, calcium signals, and subsequent F‐actin assembly.</abstract><doi>10.1002/adfm.202370217</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | axon pathfinding extracellular matrix mechanical signals synapse formation |
title | Fibrous Viscoelastic Extracellular Matrix Assists Precise Neuronal Connectivity (Adv. Funct. Mater. 36/2023) |
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