Antibiotic Delivery: In Vitro and In Vivo Antimicrobial Activity of Antibiotic‐Conjugated Carriers with Rapid pH‐Responsive Release Kinetics (Adv. Healthcare Mater. 14/2019)

In article number 1900247 by Yan Lee, Tae Hyun Choi, and co‐workers, a pH‐responsive antibiotic drug conjugate system is developed using a maleic acid amide‐based linker. The conjugate system can rapidly release the antibiotics and induce antimicrobial activities against S. aureus at weakly acidic e...

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Bibliographic Details
Published in:Advanced healthcare materials 2019-07, Vol.8 (14), p.n/a
Main Authors: Kang, Sunyoung, Park, Gee Ho, Kim, Seulah, Kim, Jungah, Choi, Yoonhwa, Huang, Yan, Lee, Yan, Choi, Tae Hyun
Format: Article
Language:English
Subjects:
antibiotics
antimicrobial activity
controlled release
drug delivery
pH‐responsiveness
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Summary:In article number 1900247 by Yan Lee, Tae Hyun Choi, and co‐workers, a pH‐responsive antibiotic drug conjugate system is developed using a maleic acid amide‐based linker. The conjugate system can rapidly release the antibiotics and induce antimicrobial activities against S. aureus at weakly acidic environments in abscesses or inflammatory tissues.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.201970058