Development of novel biosensor enzyme electrodes: Glucose oxidase multilayer arrays immobilized onto self-assembled monolayers on electrodes

Amperometric biosensors under development are based on electron transfer communication between enzyme redox sites and electrodes. These require well‐organized networks of enzymes exhibiting long‐range electron transfer properties. An enzyme electrode is described that consists of glucose oxidase net...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 1993-12, Vol.5 (12), p.912-915
Main Authors: Willner, Itamar, Riklin, Azalia, Shoham, Benjamin, Rivenzon, Dalia, Katz, Eugenii
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biosensors
Biotechnology
Chemistry
Electrochemistry
Electrodes: preparations and properties
Exact sciences and technology
Fundamental and applied biological sciences. Psychology
General and physical chemistry
Ion selective electrodes
Methods. Procedures. Technologies
Various methods and equipments
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Summary:Amperometric biosensors under development are based on electron transfer communication between enzyme redox sites and electrodes. These require well‐organized networks of enzymes exhibiting long‐range electron transfer properties. An enzyme electrode is described that consists of glucose oxidase networks organized on a self‐assembled monolayer of functionalized thiols on gold electrodes. The protein array supports electrical communication with the electrode, and the resulting assembly can be used as a glucose biosensor.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.19930051206